Perspectives for self-driving labs in synthetic biology

HG Martin, T Radivojevic, J Zucker, K Bouchard… - Current Opinion in …, 2023 - Elsevier
Highlights•Self-driving labs (SDLs) combine automated experiments with AI to direct
them.•Synthetic biology provides a unique opportunity for the development of SDLs.•The …

An outlook on the current challenges and opportunities in DNA data storage

MH Raza, S Desai, S Aravamudhan, R Zadegan - Biotechnology Advances, 2023 - Elsevier
Silicon is the gold standard for information storage systems. The exponential generation of
digital information will exhaust the global supply of refined silicon. Therefore, investing in …

A machine learning Automated Recommendation Tool for synthetic biology

T Radivojević, Z Costello, K Workman… - Nature …, 2020 - nature.com
Synthetic biology allows us to bioengineer cells to synthesize novel valuable molecules
such as renewable biofuels or anticancer drugs. However, traditional synthetic biology …

Scalable and automated CRISPR-based strain engineering using droplet microfluidics

K Iwai, M Wehrs, M Garber, J Sustarich… - Microsystems & …, 2022 - nature.com
We present a droplet-based microfluidic system that enables CRISPR-based gene editing
and high-throughput screening on a chip. The microfluidic device contains a 10× 10 element …

Role of digital microfluidics in enabling access to laboratory automation and making biology programmable

VB Kothamachu, S Zaini… - … Translating Life Sciences …, 2020 - journals.sagepub.com
Digital microfluidics (DMF) is a liquid handling technique that has been demonstrated to
automate biological experimentation in a low-cost, rapid, and programmable manner. This …

Droplet and digital microfluidics–enabled analytical techniques

K Gupta, Z Chen, K Gopinathan, A Mishra… - Droplet and Digital …, 2024 - Elsevier
Microfluidics has enabled the analysis of several biochemical phenomena crucial to life as
we know it. Encapsulation of target molecules, cells, or synthetic particles in micro and …

Miniaturized Engineering of Human Cells using Droplet Microfluidics

S Little - 2024 - spectrum.library.concordia.ca
Inserting foreign biomolecules into human cells is at the heart of cell engineering protocols.
By taking nucleic acids or fully formed proteins and shuttling them across the cell membrane …