Cell motility is essential for life and development. Unfortunately, cell migration is also linked
to several pathological processes, such as cancer metastasis. Cells' ability to migrate relies …

Hydrogel-based artificial scaffolds play a vital role in shifting in vitro models from two-
dimensional (2D) cell culture to three-dimensional (3D) cell culture. Microfluidic 3D cell …

The extracellular matrix (ECM) is a significant factor in cancer progression. Collagens, as the
main component of the ECM, are greatly remodeled alongside cancer development. More …

Extravasation of circulating cells is an essential process that governs tissue inflammation
and the body's response to pathogenic infection. To initiate anti-inflammatory and …

Macrophages play an essential role in the process of recognition and containment of
microbial infections. These immune cells are recruited to infectious sites to reach and …

The cervix acts as a dynamic barrier between the uterus and vagina, retaining the fetus
during pregnancy and allowing birth at term. Critical to this function, the physical properties …

Cell migration is essential for a variety of biological processes, such as embryogenesis,
wound healing, and the immune response. After more than a century of research—mainly on …

To exert their therapeutic effects, nanoparticles (NPs) often need to travel into the tissues
composed of multilayered cells. Accumulative evidence has revealed the crucial role of …

The recent development of bone-on-chips (BOCs) holds the main advantage of requiring a
low quantity of cells and material, compared to traditional In Vitro models. By incorporating …

In this study, we use non-linear imaging microscopy to characterize the structural properties
of porous collagen-GAG scaffolds (CGS) seeded with human umbilical vein endothelial cells …