Early life gut microbiota have been increasingly recognized as major contributors to short
and/or long-term human health and diseases. Numerous studies have demonstrated that …

Low-and middle-income countries (LMICs), particularly those in sub-Saharan Africa, are
experiencing rapid increases in the prevalence of non-communicable diseases (NCDs) …

The theory of developmental programming suggests that diseases such as the metabolic
syndrome may be 'programmed'by exposure to adverse stimuli during early development …

Exposure to stress is inevitable, and it may occur, to varying degrees, at different phases
throughout the lifespan. The impact of stress experienced in later life has been well …

Research investigating the early programming of adult metabolic disease has in recent
years provided much mechanistic insight into how the early environment impacts on long …

Cardiovascular diseases (CVDs) constitute a particular challenge during pregnancy
because physiological changes and fetal demands create an additional burden and fetal …

The intrauterine environment is a major contributor to normal physiological growth and
development of an individual. Disturbances at this critical time can affect the long-term …

Background We have shown recently that maternal undernutrition (UN) advanced female
pubertal onset in a manner that is dependent upon the timing of UN. The long-term …

The prevalence of age-associated disease is increasing at a striking rate globally. It is
known that a strong association exists between a suboptimal maternal and/or early-life …

The global epidemic of diabetes is a serious threat against health and healthcare expenses.
Although genetics is important it does not explain the dramatic increase in incidence, which …