Sequence assembly demystified
N Nagarajan, M Pop - Nature Reviews Genetics, 2013 - nature.com
Advances in sequencing technologies and increased access to sequencing services have
led to renewed interest in sequence and genome assembly. Concurrently, new applications …
led to renewed interest in sequence and genome assembly. Concurrently, new applications …
Next-generation sequence assembly: four stages of data processing and computational challenges
S El-Metwally, T Hamza, M Zakaria… - PLoS computational …, 2013 - journals.plos.org
Decoding DNA symbols using next-generation sequencers was a major breakthrough in
genomic research. Despite the many advantages of next-generation sequencers, eg, the …
genomic research. Despite the many advantages of next-generation sequencers, eg, the …
Reconstructing mitochondrial genomes directly from genomic next-generation sequencing reads—a baiting and iterative mapping approach
We present an in silico approach for the reconstruction of complete mitochondrial genomes
of non-model organisms directly from next-generation sequencing (NGS) data …
of non-model organisms directly from next-generation sequencing (NGS) data …
ALE: a generic assembly likelihood evaluation framework for assessing the accuracy of genome and metagenome assemblies
Motivation: Researchers need general purpose methods for objectively evaluating the
accuracy of single and metagenome assemblies and for automatically detecting any errors …
accuracy of single and metagenome assemblies and for automatically detecting any errors …
Identification of Optimum Sequencing Depth Especially for De Novo Genome Assembly of Small Genomes Using Next Generation Sequencing Data
Next Generation Sequencing (NGS) is a disruptive technology that has found widespread
acceptance in the life sciences research community. The high throughput and low cost of …
acceptance in the life sciences research community. The high throughput and low cost of …
A comprehensive study of de novo genome assemblers: current challenges and future prospective
AR Khan, MT Pervez, ME Babar… - Evolutionary …, 2018 - journals.sagepub.com
Background: Current advancements in next-generation sequencing technology have made
possible to sequence whole genome but assembling a large number of short sequence …
possible to sequence whole genome but assembling a large number of short sequence …
Host subtraction, filtering and assembly validations for novel viral discovery using next generation sequencing data
The use of next generation sequencing (NGS) to identify novel viral sequences from
eukaryotic tissue samples is challenging. Issues can include the low proportion and copy …
eukaryotic tissue samples is challenging. Issues can include the low proportion and copy …
[HTML][HTML] Perfluorobutane sulfonate exposure disrupted human placental cytotrophoblast cell proliferation and invasion involving in dysregulating preeclampsia related …
WP Marinello, ZS Mohseni… - … : official publication of …, 2020 - ncbi.nlm.nih.gov
We previously reported that maternal PFBS, an emerging pollutant, exposure is positively
associated with preeclampsia which can results from aberrant trophoblasts invasion and …
associated with preeclampsia which can results from aberrant trophoblasts invasion and …
An overlooked phenomenon: complex interactions of potential error sources on the quality of bacterial de novo genome assemblies
Background Parameters adversely affecting the contiguity and accuracy of the assemblies
from Illumina next-generation sequencing (NGS) are well described. However, past studies …
from Illumina next-generation sequencing (NGS) are well described. However, past studies …
In Silico Whole Genome Sequencer and Analyzer (iWGS): a Computational Pipeline to Guide the Design and Analysis of de novo Genome Sequencing Studies
The availability of genomes across the tree of life is highly biased toward vertebrates,
pathogens, human disease models, and organisms with relatively small and simple …
pathogens, human disease models, and organisms with relatively small and simple …