Site-selective functionalization of hydroxyl groups in carbohydrate derivatives

V Dimakos, MS Taylor - Chemical reviews, 2018 - ACS Publications
Methods for site-selective transformations of hydroxyl groups in carbohydrate derivatives are
reviewed. The construction of oligosaccharides of defined connectivity hinges on such …

Exploiting non-covalent interactions in selective carbohydrate synthesis

CCJ Loh - Nature Reviews Chemistry, 2021 - nature.com
Non-covalent interactions (NCIs) are a vital component of biological bond-forming events,
and have found important applications in multiple branches of chemistry. In recent years, the …

Scale-up of a Heck alkenylation reaction: Application to the synthesis of an amino-modifier nucleoside 'Ruth linker'

S Bhilare, S Kori, H Shet, G Balaram, K Mahendar… - …, 2020 - thieme-connect.com
Ruth linker is a C5 pyrimidine modified nucleoside analogue widely utilized for the
incorporation of a primary amine in a synthetic oligonucleotide. The increasing demand for …

New strategies for hydroxyl-directed organic reactions

TP Blaisdell - 2015 - search.proquest.com
Described herein are four different research projects spanning over two different research
groups. The first two projects describe the development and application of scaffolding …