The Chinese medicinal plant Artemisia annua L.(Qinghao) is the only known source of the
sesquiterpene artemisinin (Qinghaosu), which is used in the treatment of malaria …

Nerolidol and Davanone Derivatives Bisabolene Derivatives Germacranes and
Germacranolides Eudesmanes and Eudesmanolides Guaianes and Guaianolides Other …

The treatment of artemisinin (1) and β‐artemether (6) with Zn dissolving in AcOH for a few
hours results in mono‐deoxygenation giving deoxyartemisinin (5) and deoxy‐β‐artemether …

Artemisia annua L. contains artemisinin, an endoperoxide sesquiterpene lactone, mainly in
its leaves and inflorescences. This compound and a series of derivatives have attracted …

EPR experiments confirm that reaction of qinghaosu and some related endoperoxides with
Fe2+ in aqueous acetonitrile leads to the production of carbon-centred radicals derived by …

Noncompetitive inhibitors of sarco/endoplasmic reticulum Ca 2+-ATPase (SERCA)
orthologue (PfATP6) of P. falciparum have important therapeutic value in the treatment of …

Quantum chemical calculations on the molecular electronic structure of artemisinin
(qinghaosu) and eight of its derivatives have resulted in stereoelectronic discriminators that …

Malaria is an infectious disease caused by the unicellular parasite Plasmodium sp.
Currently, the malaria parasite is becoming resistant to the traditional pharmacological …

Artemisinin and some derivatives with activity against D-6 strains of Plasmodium falciparum
were studied. Molecular electrostatic potential (MEP) maps were used in an attempt to …

The purpose of this chapter is to review the phytochemistry of Artemisia annua and to
discuss the biosynthesis, extraction and isolation of artemisinin as well as derivatives of …