Pyroptosis: mechanisms and diseases

P Yu, X Zhang, N Liu, L Tang, C Peng… - Signal transduction and …, 2021 - nature.com
Currently, pyroptosis has received more and more attention because of its association with
innate immunity and disease. The research scope of pyroptosis has expanded with the …

Roles and mechanisms of exosomal non-coding RNAs in human health and diseases

C Li, YQ Ni, H Xu, QY Xiang, Y Zhao, JK Zhan… - Signal transduction and …, 2021 - nature.com
Exosomes play a role as mediators of cell-to-cell communication, thus exhibiting pleiotropic
activities to homeostasis regulation. Exosomal non-coding RNAs (ncRNAs), mainly …

Liquid biopsy at the frontier of detection, prognosis and progression monitoring in colorectal cancer

H Zhou, L Zhu, J Song, G Wang, P Li, W Li, P Luo… - Molecular cancer, 2022 - Springer
Colorectal cancer (CRC) is one of the most common cancers worldwide and a leading
cause of carcinogenic death. To date, surgical resection is regarded as the gold standard by …

Exosomal circRNA: emerging insights into cancer progression and clinical application potential

F Zhang, J Jiang, H Qian, Y Yan, W Xu - Journal of Hematology & …, 2023 - Springer
Exosomal circRNA serves a novel genetic information molecule, facilitating communication
between tumor cells and microenvironmental cells, such as immune cells, fibroblasts, and …

Exosomal circLPAR1 functions in colorectal cancer diagnosis and tumorigenesis through suppressing BRD4 via METTL3–eIF3h interaction

R Zheng, K Zhang, S Tan, F Gao, Y Zhang, W Xu… - Molecular cancer, 2022 - Springer
Background Exosomes have emerged as vital biomarkers of multiple cancers and contain
abundant circular RNAs (circRNAs). However, the potential for exosomal circRNAs to be …

Essential roles of exosome and circRNA_101093 on ferroptosis desensitization in lung adenocarcinoma

X Zhang, Y Xu, L Ma, K Yu, Y Niu, X Xu… - Cancer …, 2022 - Wiley Online Library
Background Resistance to ferroptosis, a regulated cell death caused by iron‐dependent
excessive accumulation of lipid peroxides, has recently been linked to lung adenocarcinoma …

CircEZH2/miR-133b/IGF2BP2 aggravates colorectal cancer progression via enhancing the stability of m6A-modified CREB1 mRNA

B Yao, Q Zhang, Z Yang, F An, H Nie, H Wang, C Yang… - Molecular cancer, 2022 - Springer
Background Aberrant expression of circular RNAs (circRNAs) contributes to the initiation
and progression of human malignancies, but the underlying mechanisms remain largely …

Extracellular vesicles and particles impact the systemic landscape of cancer

S Lucotti, CM Kenific, H Zhang, D Lyden - The EMBO journal, 2022 - embopress.org
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …

A novel protein encoded by exosomal CircATG4B induces oxaliplatin resistance in colorectal cancer by promoting autophagy

Z Pan, J Zheng, J Zhang, J Lin, J Lai, Z Lyu… - Advanced …, 2022 - Wiley Online Library
Oxaliplatin is commonly used in chemotherapeutic regimens for colorectal cancer (CRC)
after surgical resection. However, acquired chemoresistance seriously affects the curative …

CircOGDH is a penumbra biomarker and therapeutic target in acute ischemic stroke

Y Liu, Y Li, J Zang, T Zhang, Y Li, Z Tan, D Ma… - Circulation …, 2022 - Am Heart Assoc
Background: Acute ischemic stroke (AIS) is a leading cause of disability and mortality
worldwide. Prediction of penumbra existence after AIS is crucial for making decision on …