Despite a longstanding and widespread influence of the diagnostic approach to mental ill
health, there is an emerging and growing consensus that such psychiatric nosologies may …

In both child and adult psychiatry, empirical evidence has now accrued to suggest that a
single dimension is able to measure a person's liability to mental disorder, comorbidity …

Autism spectrum disorder (ASD) is a highly heritable and heterogeneous group of
neurodevelopmental phenotypes diagnosed in more than 1% of children. Common genetic …

The reliability and validity of traditional taxonomies are limited by arbitrary boundaries
between psychopathology and normality, often unclear boundaries between disorders …

We conducted a cross-trait meta-analysis of genome-wide association study on
schizophrenia (SCZ)(n= 65,967), bipolar disorder (BD)(n= 41,653), autism spectrum …

The Hierarchical Taxonomy of Psychopathology (HiTOP) is a scientific effort to address
shortcomings of traditional mental disorder diagnoses, which suffer from arbitrary …

For over a century, psychiatric disorders have been defined by expert opinion and clinical
observation. The modern DSM has relied on a consensus of experts to define categorical …

Abstract The Adolescent Brain Cognitive Development (ABCD) Study is the largest single-
cohort prospective longitudinal study of neurodevelopment and children's health in the …

We propose a taxonomy of psychopathology based on patterns of shared causal influences
identified in a review of multivariate behavior genetic studies that distinguish genetic and …

There is consistent evidence that mood disorders often co‐occur with anxiety disorders,
however, the strength of the association of these two broad groups of disorders has been …