Venom evolution through gene duplications

ESW Wong, K Belov - Gene, 2012 - Elsevier
Venoms contain highly complex mixtures that typically include hundreds of different
components and have evolved independently in a diverse range of animals including …

Ecological venomics: How genomics, transcriptomics and proteomics can shed new light on the ecology and evolution of venom

K Sunagar, D Morgenstern, AM Reitzel, Y Moran - Journal of Proteomics, 2016 - Elsevier
Animal venom is a complex cocktail of bioactive chemicals that traditionally drew interest
mostly from biochemists and pharmacologists. However, in recent years the evolutionary …

The venom-gland transcriptome of the eastern diamondback rattlesnake (Crotalus adamanteus)

DR Rokyta, AR Lemmon, MJ Margres, K Aronow - BMC genomics, 2012 - Springer
Background Snake venoms have significant impacts on human populations through the
morbidity and mortality associated with snakebites and as sources of drugs, drug leads, and …

Discovery and characterization of novel cyclotides originated from chimeric precursors consisting of albumin-1 chain a and cyclotide domains in the Fabaceae family

GKT Nguyen, S Zhang, NTK Nguyen… - Journal of Biological …, 2011 - ASBMB
The tropical plant Clitoria ternatea is a member of the Fabaceae family well known for its
medicinal values. Heat extraction of C. ternatea revealed that the bioactive fractions …

Revisiting venom of the sea anemone Stichodactyla haddoni: Omics techniques reveal the complete toxin arsenal of a well-studied sea anemone genus

B Madio, EAB Undheim, GF King - Journal of Proteomics, 2017 - Elsevier
More than a century of research on sea anemone venoms has shown that they contain a
diversity of biologically active proteins and peptides. However, recent omics studies have …

Expression of venom gene homologs in diverse python tissues suggests a new model for the evolution of snake venom

J Reyes-Velasco, DC Card, AL Andrew… - Molecular biology …, 2015 - academic.oup.com
Snake venom gene evolution has been studied intensively over the past several decades,
yet most previous studies have lacked the context of complete snake genomes and the full …

The first venomous crustacean revealed by transcriptomics and functional morphology: remipede venom glands express a unique toxin cocktail dominated by …

BM von Reumont, A Blanke, S Richter… - Molecular biology …, 2014 - academic.oup.com
Animal venoms have evolved many times. Venomous species are especially common in
three of the four main groups of arthropods (Chelicerata, Myriapoda, and Hexapoda), which …

A Polychaete's Powerful Punch: Venom Gland Transcriptomics of Glycera Reveals a Complex Cocktail of Toxin Homologs

BM von Reumont, LI Campbell, S Richter… - Genome Biology and …, 2014 - academic.oup.com
Glycerids are marine annelids commonly known as bloodworms. Bloodworms have an
eversible proboscis adorned with jaws connected to venom glands. Bloodworms prey on …

Extreme diversity of scorpion venom peptides and proteins revealed by transcriptomic analysis: implication for proteome evolution of scorpion venom arsenal

Y Ma, Y He, R Zhao, Y Wu, W Li, Z Cao - Journal of proteomics, 2012 - Elsevier
Venom is an important genetic development crucial to the survival of scorpions for over
400million years. We studied the evolution of the scorpion venom arsenal by means of …

Venomous mammals: a review

R Ligabue-Braun, H Verli, CR Carlini - Toxicon, 2012 - Elsevier
The occurrence of venom in mammals has long been considered of minor importance, but
recent fossil discoveries and advances in experimental techniques have cast new light into …