Bioinspired nanotopographical design of drug delivery systems

JA Finbloom, C Huynh, X Huang… - Nature Reviews …, 2023 - nature.com
Effective drug delivery is important in the treatment of various biomedical conditions, ranging
from autoimmune disorders to cancer and bacterial infections. Nanostructured systems can …

[HTML][HTML] Biomaterials to enhance stem cell transplantation

BN Kharbikar, P Mohindra, TA Desai - Cell Stem Cell, 2022 - cell.com
The successful transplantation of stem cells has the potential to transform regenerative
medicine approaches and open promising avenues to repair, replace, and regenerate …

[Retracted] Inflammation and Oxidative Stress Role of S100A12 as a Potential Diagnostic and Therapeutic Biomarker in Acute Myocardial Infarction

J Xie, C Luo, B Mo, Y Lin, G Liu… - Oxidative medicine and …, 2022 - Wiley Online Library
Acute myocardial infarction (AMI) is one of the most serious cardiovascular diseases with
high morbidity and mortality. Numerous studies have indicated that S100A12 may has an …

Dendrimers in neurodegenerative diseases

MD Pérez-Carrión, I Posadas - Processes, 2023 - mdpi.com
Neurodegenerative diseases (NDs), such as Parkinson's Disease (PD), Alzheimer's Disease
(AD), Multiple Sclerosis (MS) and amyotrophic lateral sclerosis (ALS), are characterized by …

Local decorin delivery via hyaluronic acid microrods improves cardiac performance, ventricular remodeling after myocardial infarction

P Mohindra, JX Zhong, Q Fang, DL Cuylear… - NPJ Regenerative …, 2023 - nature.com
Heart failure (HF) remains a global public health burden and often results following
myocardial infarction (MI). Following injury, cardiac fibrosis forms in the myocardium which …

Mechanisms of acrolein induces toxicity in human umbilical vein endothelial cells: Oxidative stress, DNA damage response, and apoptosis

D Liu, Y Cheng, X Mei, Y Xie, Z Tang… - Environmental …, 2022 - Wiley Online Library
Acrolein is a ubiquitous environmental pollutant that produced by the incomplete
combustion of cigarette smoke, forest fires, petroleum fuels, plastic materials, and cooking …

Nanomaterials for small diameter vascular grafts: overview and outlook

N Wang, H Wang, D Weng, Y Wang, L Yu… - Nanoscale …, 2023 - pubs.rsc.org
Small-diameter vascular grafts (SDVGs) cannot meet current clinical demands owing to their
suboptimal long-term patency rate. Various materials have been employed to address this …

The role of a nanogrooved polydimethylsiloxane substrate on mesenchymal stem cells adhesion, self-renewing, and mechanical properties

R Mahdavian, N Hashemi, M Sedghi… - Colloids and Surfaces A …, 2023 - Elsevier
Stem cells have a variety of applications in biological, reconstructive medicine, and tissue
engineering studies owing to their capacity to differentiate into specific cell lineages and …

Aligned nanofibrous net deposited perpendicularly on microridges supports endothelium formation and promotes the structural maturation of hiPSC-derived …

F Tian, L Yin, P Lin, Y Liu, W Wang… - ACS Applied Materials …, 2023 - ACS Publications
Cell alignment widely exists in various in vivo tissues and also plays an essential role in the
construction of in vitro models, such as vascular endothelial and myocardial models …

The Effects of Biomimetic Surface Topography on Vascular Cells: Implications for Vascular Conduits

AA Conner, D David, EKF Yim - Advanced Healthcare …, 2024 - Wiley Online Library
Cardiovascular diseases (CVDs) are the leading cause of mortality worldwide and represent
a pressing clinical need. Vascular occlusions are the predominant cause of CVD and …