Over the past two decades, significant progress in understanding of the pathogenesis of type
2 chronic inflammatory diseases has enabled the identification of compounds for more than …

Chronic spontaneous urticaria (CSU) is a debilitating skin disease characterized by
intensely itchy wheals, angioedema, or both. Symptoms recur spontaneously, on a near …

Chronic urticaria (CU) is a mast cell (MC)‐dependent disease with limited therapeutic
options. Current management strategies are directed at inhibiting IgE‐mediated activation of …

BACKGROUND IgE-mediated anaphylaxis is a potentially fatal systemic allergic reaction for
which there are no currently FDA-approved preventative therapies. Bruton's tyrosine kinase …

Chronic urticaria is a common and debilitating mast cell-driven skin disease presenting with
itchy wheals, angio-oedema, or both. Chronic urticaria is classified as spontaneous (without …

Chronic spontaneous urticaria (CSU) is primarily a T2-dominant disease with a complex
genetic background. Skin mast cell activation can be induced not only via the IgE-FcεRI axis …

Chronic spontaneous urticaria (CSU) is an inflammatory skin disorder that manifests with
itchy wheals, angioedema, or both for more than 6 weeks. Mast cells and basophils are the …

Chronic spontaneous urticaria (CSU) is a condition in which wheals, angioedema, and
pruritus occur spontaneously and recurrently for at least 6 weeks. The etiology of this …

Abstract Purpose of Review Chronic inducible urticaria (CIndU) is a group of long-persisting
and challenging to manage diseases, characterized by recurrent wheals and angioedema …

Importance Chronic spontaneous urticaria affects approximately 1% of the general
population worldwide, including approximately 3 million people in the US, impairs patients' …