Neurons are highly polarized cells that rely on the intracellular transport of organelles. This
process is regulated by molecular motors such as dynein and kinesins and the Rab family of …

Axons are processes of neurons, up to a metre long, that form the essential biological cables
wiring nervous systems. They must survive, often far away from their cell bodies and up to a …

Investigating the molecular mechanisms governing developmental axon growth has been a
useful approach for identifying new strategies for boosting axon regeneration after injury …

The polarized cell morphology of neurons dictates many neuronal processes, including the
axodendridic transport of specific mRNAs and subsequent translation. mRNAs together with …

Endosomal cargo recycling lies at the heart of subcellular trafficking processes under the
management of several Ras‐related GTP‐binding proteins (Rabs) which are coordinated by …

Among the plethora of defense mechanisms which a host elicits after pathogen invasion,
type 1 interferons play a central role in regulating the immune system's response. They …

Abstract Development of the mammalian neocortex requires proper inside‐out migration of
developing cortical neurons from the germinal ventricular zone toward the cortical plate. The …

During intracellular trafficking N-ethylmaleimide-sensitive-factor attachment receptor
(SNARE) proteins catalyze the membrane fusion by assembling into a four-helix complex. In …

Chromodomain helicase DNA binding domain (CHD) proteins, including CHD7 and CHD8,
remodel chromatin to enable transcriptional programs. Both proteins are important for proper …

Rab35 (Ras-associated binding protein) is a small GTPase that regulates endosomal
membrane trafficking and functions in cell polarity, cytokinesis, and growth factor signaling …