Comet assay: a reliable tool for the assessment of DNA damage in different models
A Dhawan, M Bajpayee, D Parmar - Cell biology and toxicology, 2009 - Springer
New chemicals are being added each year to the existing burden of toxic substances in the
environment. This has led to increased pollution of ecosystems as well as deterioration of …
environment. This has led to increased pollution of ecosystems as well as deterioration of …
An investigation of DNA damage and DNA repair in chemical carcinogenesis triggered by small-molecule xenobiotics and in cancer: Thirty years with the comet assay
P Vodicka, S Vodenkova, J Horak, A Opattova… - … /Genetic Toxicology and …, 2023 - Elsevier
In the present review we addressed the determination of DNA damage induced by small-
molecule carcinogens, considered their persistence in DNA and mutagenicity in in vitro and …
molecule carcinogens, considered their persistence in DNA and mutagenicity in in vitro and …
Nucleotide excision repair eliminates unique DNA-protein cross-links from mammalian cells
DJ Baker, G Wuenschell, L Xia, J Termini… - Journal of Biological …, 2007 - ASBMB
DNA-protein cross-links (DPCs) present a formidable obstacle to cellular processes
because they are" superbulky" compared with the majority of chemical adducts. Elimination …
because they are" superbulky" compared with the majority of chemical adducts. Elimination …
Selenium and GPx-1 overexpression protect mammalian cells against UV-induced DNA damage
MS Baliga, H Wang, P Zhuo, JL Schwartz… - Biological trace element …, 2007 - Springer
Supplementation of the culture media of human MCF-7 breast carcinoma cells or mouse
fibroblasts with low levels of selenium (30 n M) provided as sodium selenite was shown to …
fibroblasts with low levels of selenium (30 n M) provided as sodium selenite was shown to …
Genotoxic risk assessment of pathology and anatomy laboratory workers exposed to formaldehyde by use of personal air sampling and analysis of DNA damage in …
T Orsière, I Sari-Minodier, G Iarmarcovai… - … /Genetic Toxicology and …, 2006 - Elsevier
A study was conducted to evaluate the genotoxic effect of occupational exposure to
formaldehyde on pathology and anatomy laboratory workers. The level of exposure to …
formaldehyde on pathology and anatomy laboratory workers. The level of exposure to …
Cytogenetic analysis of nasal mucosa cells and lymphocytes from high-level long-term formaldehyde exposed workers and low-level short-term exposed waiters
X Ye, W Yan, H Xie, M Zhao, C Ying - Mutation Research/Genetic …, 2005 - Elsevier
The evidence for genotoxic potential of formaldehyde (FA) in humans is insufficient and
conflicting. We previously reported a higher frequency of micronuclei in nasal and oral …
conflicting. We previously reported a higher frequency of micronuclei in nasal and oral …
Increased levels of chromosomal aberrations and DNA damage in a group of workers exposed to formaldehyde
Formaldehyde (FA) is a commonly used chemical in anatomy and pathology laboratories as
a tissue preservative and fixative. Because of its sensitising properties, irritating effects and …
a tissue preservative and fixative. Because of its sensitising properties, irritating effects and …
Oxidative effects on lung inflammatory response in rats exposed to different concentrations of formaldehyde
GL Murta, KKD Campos, ACB Bandeira, MF Diniz… - Environmental …, 2016 - Elsevier
The formaldehyde (FA) is a crosslinking agent that reacts with cellular macromolecules such
as proteins, nucleic acids and molecules with low molecular weight such as amino acids …
as proteins, nucleic acids and molecules with low molecular weight such as amino acids …
Combining a microphysiological system of three organ equivalents and transcriptomics to assess toxicological endpoints for cosmetic ingredients
N de Carvalho Indolfo, MD Ganzerla, TR Doratioto… - Lab on a Chip, 2023 - pubs.rsc.org
Animal testing for cosmetic ingredients and final products has been banned in Europe and is
gaining legal force worldwide. However, the need for reliable testing methodologies remains …
gaining legal force worldwide. However, the need for reliable testing methodologies remains …
Cytotoxicity of hard chairside reline resins: effect of microwave irradiation and water bath postpolymerization treatments.
NH Campanha, AC Pavarina… - International journal …, 2006 - search.ebscohost.com
Purpose: To evaluate the influence of water bath and microwave postpolymerization
treatments on the cytotoxicity of 6 hard reline acrylic resins. Materials and Methods: The …
treatments on the cytotoxicity of 6 hard reline acrylic resins. Materials and Methods: The …