Chitosan-based biomaterials: insights into chemistry, properties, devices, and their biomedical applications

S Petroni, I Tagliaro, C Antonini, M D'Arienzo, SF Orsini… - Marine drugs, 2023 - mdpi.com
Chitosan is a marine-origin polysaccharide obtained from the deacetylation of chitin, the
main component of crustaceans' exoskeleton, and the second most abundant in nature …

[HTML][HTML] Injectable hydrogels: An emerging therapeutic strategy for cartilage regeneration

A Atwal, TP Dale, M Snow, NR Forsyth… - Advances in colloid and …, 2023 - Elsevier
The impairment of articular cartilage due to traumatic incidents or osteoarthritis has posed
significant challenges for healthcare practitioners, researchers, and individuals suffering …

Advanced injectable hydrogels for cartilage tissue engineering

S Zhu, Y Li, Z He, L Ji, W Zhang, Y Tong… - … in bioengineering and …, 2022 - frontiersin.org
The rapid development of tissue engineering makes it an effective strategy for repairing
cartilage defects. The significant advantages of injectable hydrogels for cartilage injury …

Developments on the Smart Hydrogel-Based Drug Delivery System for Oral Tumor Therapy

Y Zhao, B Ran, X Xie, W Gu, X Ye, J Liao - Gels, 2022 - mdpi.com
At present, an oral tumor is usually treated by surgery combined with preoperative or
postoperative radiotherapies and chemotherapies. However, traditional chemotherapies …

Smart injectable chitosan hydrogels loaded with 5-fluorouracil for the treatment of breast cancer

AAH Abdellatif, AM Mohammed, I Saleem… - Pharmaceutics, 2022 - mdpi.com
The treatment of breast cancer requires long chemotherapy management, which is
accompanied by severe side effects. Localized delivery of anticancer drugs helps to …

Injectable thermogel incorporating reactive oxygen species scavenger and nitric oxide donor to accelerate the healing process of diabetic wounds

THT Do, TKT Pham, PT Ha, TP Nguyen, TP Dao… - International Journal of …, 2023 - Elsevier
The healing of diabetic wounds is challenging due to redox imbalances. Herein, the
thermogelling system AR-ACP hydrogel, with encapsulated biosafe nitric oxide (NO) donor L …

Smart polymeric micelles for anticancer hydrophobic drugs

A Guzmán Rodríguez, M Sablón Carrazana… - Cancers, 2022 - mdpi.com
Simple Summary Cancer has been a lethal and high-incidence disease for many years and
its cure is characterized by invasive methods and with notable side effects. Nanotechnology …

Injectable thermoresponsive hydrogels for cancer therapy: challenges and prospects

S Tanga, M Aucamp, P Ramburrun - Gels, 2023 - mdpi.com
The enervating side effects of chemotherapeutic drugs have necessitated the use of targeted
drug delivery in cancer therapy. To that end, thermoresponsive hydrogels have been …

Temperature induced gelation and antimicrobial properties of Pluronic F127 based systems

A Lupu, I Rosca, VR Gradinaru, M Bercea - Polymers, 2023 - mdpi.com
Different formulations containing Pluronic F127 and polysaccharides (chitosan, sodium
alginate, gellan gum, and κ-carrageenan) were investigated as potential injectable gels that …

Synthesis, properties, and applications of chitosan hydrogels as anti-inflammatory drug delivery system

HTT Nguyen, NHN Do, HD Lac, PLN Nguyen… - Journal of Porous …, 2023 - Springer
As a chitin-and glucosamine-derived polysaccharide, chitosan is biodegradable,
biocompatible, and non-toxic. Among the latest high-value engineering materials, chitosan …