To infect the host and cause disease, many medically important fungi invade normally
nonphagocytic host cells, such as endothelial cells and epithelial cells. Host cell invasion is …

Spliceosomal introns are noncoding sequences that are spliced from pre-mRNA. They are
ubiquitous in eukaryotic genomes, although the average number of introns per gene varies …

Oral epithelial cells discriminate between pathogenic and non-pathogenic stimuli, and only
induce an inflammatory response when they are exposed to high levels of a potentially …

Exopolysaccharide (EPS) from marine microalgae are promising sources of a new
generation of drugs. However, lot of them remain to be discovered and tested. In this study …

Haemophilus influenzae is a Gram negative bacterium that belongs to the family
Pasteurellaceae, causes bacteremia, pneumonia and acute bacterial meningitis in infants …

Background Antimicrobial peptides have been the focus of much research over the last
decade because of their effectiveness and broad-spectrum activity against microbial …

Serine/arginine-rich (SR) proteins are well known as splicing factors in humans, model
animals and plants. However, they are largely unknown in regulating pre-mRNA splicing of …

Shigella flexneri is the principal cause of bacillary dysentery, contributing significantly to the
global burden of diarrheal disease. The appearance and increase in the multi-drug …

To cause disease, a microbial pathogen must adapt to the challenges of its host
environment. The leading fungal pathogen Candida albicans colonizes nutrient-poor bodily …

Yeast can be engineered into “living foundries” for non-natural chemical production by
reprogramming them via a “design-build-test” cycle. While methods for “design” and “build” …