Detection of minimal residual disease (MRD) has proven to provide independent prognostic
information for treatment stratification in several types of leukemias such as childhood acute …

Prospective studies on the detection of minimal residual disease (MRD) in acute leukemia
patients have shown that large-scale MRD studies are feasible and that clinically relevant …

Chronic myeloid leukemia (CML) is genetically characterized by the presence of the
reciprocal translocation t (9; 22)(q34; q11), resulting in a BCR/ABL gene fusion on the …

Constitutive activation of tyrosine kinases, such as the BCR/ABL fusion associated with t (9;
22)(q34; q22), is a hallmark of chronic myeloid leukemia (CML) syndromes in humans …

Detection of minimal residual disease is recognized as an important post‐therapy risk factor
in acute myeloid leukemia patients. Two most commonly used methods for residual disease …

To evaluate the prognostic significance of quantitative PML-RARA, AML1-ETO, and CBFB-
MYH11 fusion transcript expression, real-time polymerase chain reaction was used to …

We have previously reported that leukemic dendritic cells (DC) can be generated ex vivo
from myelomonocytic precursors in chronic myelogenous leukemia. In this study we report …

Purpose: Genetic changes in sporadic ovarian cancer are relatively poorly characterized
compared with other tumor types. We have evaluated the use of high-resolution whole …

Abstract 16; 21 translocation is a recurrent primary abnormality in acute myeloid leukemia
(AML). The genes involved in this translocation are ERG on chromosome 21 and TLS/FUS …

Acute myeloid leukaemia (AML) has been proposed to arise from the collaboration between
two classes of mutation, a class I, or proliferative, mutation and a class II, or blocking …