Human Mn-superoxide dismutase inactivation by peroxynitrite: a paradigm of metal-catalyzed tyrosine nitration in vitro and in vivo

V Demicheli, DM Moreno, R Radi - Metallomics, 2018 - academic.oup.com
Human MnSOD is a homotetramer and represents an essential mitochondrial antioxidant
enzyme, which catalyzes the dismutation of superoxide radicals (O2˙−) at near diffusion …

Novel mechanisms for superoxide-scavenging activity of human manganese superoxide dismutase determined by the K68 key acetylation site

J Lu, K Cheng, B Zhang, H Xu, Y Cao, F Guo… - Free Radical Biology …, 2015 - Elsevier
Superoxide is the primary reactive oxygen species generated in the mitochondria.
Manganese superoxide dismutase (SOD2) is the major enzymatic superoxide scavenger …

Redox regulation of the superoxide dismutases SOD3 and SOD2 in the pulmonary circulation

D Hernandez-Saavedra, K Swain, R Tuder… - … Redox Signaling in …, 2017 - Springer
When evaluating the role of redox-regulating signaling in pulmonary vascular diseases, it is
intriguing to consider the modulation of key antioxidant enzymes like superoxide dismutase …

Tetramerization reinforces the dimer interface of MnSOD

Y Sheng, A Durazo, M Schumacher, EB Gralla… - PLoS …, 2013 - journals.plos.org
Two yeast manganese superoxide dismutases (MnSOD), one from Saccharomyces
cerevisiae mitochondria (Sc MnSOD) and the other from Candida albicans cytosol (Ca …

Effect of S-nitrosoglutathione on renal mitochondrial function: a new mechanism for reversible regulation of manganese superoxide dismutase activity?

NK Patil, H Saba, LA MacMillan-Crow - Free Radical Biology and Medicine, 2013 - Elsevier
Mitochondria are at the heart of all cellular processes as they provide the majority of the
energy needed for various metabolic processes. Nitric oxide has been shown to have …

Relationship and structural diversity of bacterial manganese superoxide dismutases and the strategy for its application in therapy and cosmetics

DS Retnoningrum - Microbiology Indonesia, 2021 - jurnal.permi.or.id
Manganese superoxide dismutase (MnSOD) from bacteria shares high amino acid
sequence homology and nearly identical structure. Despite of that, their characteristics are …

Antioxidační enzymy v srdci

L Kletečková - 2010 - dspace.cuni.cz
Kardiovaskulární onemocnění jsou jednou z nejčastějších příčin morbidity a mortality ve
vyspělých zemích. Zvýšený oxidační stres je spojen s vývojem srdečních chorob …

[引用][C] Nitración de proteínas mitocondriales: estudios estructurales y funcionales en especies nitradas de citocromo cy superóxido dismutasa de magneso

V Demicheli Dege - 2012 - Udelar. FQ