Hydrogel for bone microenvironment: Strategy and application
G Li, D Zhou, S Sheng, Q Lin, Y Jing, X Ren… - Chemical Engineering …, 2024 - Elsevier
Hydrogels, owing to their exceptional properties, are increasingly recognized in
biomedicine, particularly in tissue engineering, drug delivery, and cell scaffold …
biomedicine, particularly in tissue engineering, drug delivery, and cell scaffold …
Bone targeted nano-drug and nano-delivery
Y Wu, B Sun, Y Tang, A Shen, Y Lin, X Zhao, J Li… - Bone Research, 2024 - nature.com
There are currently no targeted delivery systems to satisfactorily treat bone-related
disorders. Many clinical drugs consisting of small organic molecules have a short circulation …
disorders. Many clinical drugs consisting of small organic molecules have a short circulation …
Tricarboxylic Acid Cycle Regulation of Metabolic Program, Redox System, and Epigenetic Remodeling for Bone Health and Disease
WS Lian, RW Wu, YH Lin, YS Chen, H Jahr, FS Wang - Antioxidants, 2024 - mdpi.com
Imbalanced osteogenic cell-mediated bone gain and osteoclastic remodeling accelerates
the development of osteoporosis, which is the leading risk factor of disability in the elderly …
the development of osteoporosis, which is the leading risk factor of disability in the elderly …
Nitric oxide contributes to rapid sclerostin protein loss following mechanical load
In response to mechanical loading of bone, osteocytes produce nitric oxide (NO•) and
decrease sclerostin protein expression, leading to an increase in bone mass. However, it is …
decrease sclerostin protein expression, leading to an increase in bone mass. However, it is …
Piezo1 Promotes Osteogenesis Through C a MKII Signalling in a Rat Maxillary Expansion Model
Z He, Y Du, C Peng, B Xu, J Tang… - Orthodontics & …, 2024 - Wiley Online Library
Objectives Rapid maxillary expansion (RME) is a widely used technique to treat maxillary
transverse deficiency. Piezo1 is a cation channel that is activated by mechanical force and …
transverse deficiency. Piezo1 is a cation channel that is activated by mechanical force and …
[HTML][HTML] Osteoblast-derived extracellular vesicles exert bone formation effects by WIF1-mediated regulation of mitophagy
Y Gu, J Zhao, J Wang, Y Jiang, Y Jing, K Xu, J Su - Medicine Plus, 2024 - Elsevier
Background Osteoporosis arises mainly from an imbalance in bone remodeling,
characterized by the impaired ability of osteoblasts (OBs) to form new bone. A significant …
characterized by the impaired ability of osteoblasts (OBs) to form new bone. A significant …