“Platinum resistant” ovarian cancer: what is it, who to treat and how to measure benefit?

A Davis, AV Tinker, M Friedlander - Gynecologic oncology, 2014 - Elsevier
Abstract “Platinum resistant” ovarian cancer was historically defined as disease recurrence
within 6 months of completion of first-line platinum-based chemotherapy, although this is …

Early versus delayed treatment of relapsed ovarian cancer (MRC OV05/EORTC 55955): a randomised trial

GJS Rustin, MEL Van Der Burg, CL Griffin, D Guthrie… - The Lancet, 2010 - thelancet.com
Background Serum CA125 concentration often rises several months before clinical or
symptomatic relapse in women with ovarian cancer. In the MRC OV05/EORTC 55955 …

HE4 as a biomarker for ovarian and endometrial cancer management

J Li, S Dowdy, T Tipton, K Podratz, WG Lu… - Expert review of …, 2009 - Taylor & Francis
Ovarian and endometrial cancer will be diagnosed in over 63,000 women in 2009, resulting
in 22,000 deaths in the USA. Histologic screening, such as pap smears for detection of …

[HTML][HTML] Short O-GalNAc glycans: regulation and role in tumor development and clinical perspectives

J Chia, G Goh, F Bard - Biochimica Et Biophysica Acta (BBA)-General …, 2016 - Elsevier
Background While the underlying causes of cancer are genetic modifications, changes in
cellular states mediate cancer development. Tumor cells display markedly changed …

Claudin-containing exosomes in the peripheral circulation of women with ovarian cancer

J Li, CA Sherman-Baust, M Tsai-Turton, RE Bristow… - BMC cancer, 2009 - Springer
Background The absence of highly sensitive and specific serum biomarkers makes mass
screening for ovarian cancer impossible. The claudin proteins are frequently overexpressed …

An update on the role of PET/CT and PET/MRI in ovarian cancer

B Khiewvan, DA Torigian, S Emamzadehfard… - European journal of …, 2017 - Springer
This review article summarizes the role of PET/CT and PET/MRI in ovarian cancer. With
regard to the diagnosis of ovarian cancer, the presence of FDG uptake within the ovary of a …

HE 4 and CA 125 levels in the preoperative assessment of endometrial cancer patients: a prospective multicenter study (ENDOMET)

SL Antonsen, E Høgdall, IJ Christensen… - Acta obstetricia et …, 2013 - Wiley Online Library
Objective To evaluate whether human epididymis protein 4 (HE 4) and CA 125 correlate
with known high‐risk prognostic factors for endometrial cancer. Design Prospective …

Proteomic analysis of ovarian cancer cells reveals dynamic processes of protein secretion and shedding of extra-cellular domains

VM Faça, AP Ventura, MP Fitzgibbon, SR Pereira-Faça… - PloS one, 2008 - journals.plos.org
Background Elucidation of the repertoire of secreted and cell surface proteins of tumor cells
is relevant to molecular diagnostics, tumor imaging and targeted therapies. We have …

Clinical potential of mucins in diagnosis, prognosis, and therapy of ovarian cancer

AP Singh, S Senapati, MP Ponnusamy, M Jain… - The lancet …, 2008 - thelancet.com
Knowledge of mucins and their multiple roles in various normal and pathological processes
has improved greatly in the past two decades. Mucins belong to a family of glycoproteins …

A novel electrochemical sensor for monitoring ovarian cancer tumor protein CA 125 on benzothiophene derivative based electrodes

OF Er, H Kivrak, O Ozok, S Çelik, A Kivrak - Journal of Electroanalytical …, 2022 - Elsevier
COVID-19 crisis affects ovarium cancer patients seriously. Thus, it is vital to diagnose
ovarium cancer, one of the most common types of cancer diagnosed and the causes of …