[HTML][HTML] Global and regional prevalence of multimorbidity in the adult population in community settings: a systematic review and meta-analysis

SR Chowdhury, DC Das, TC Sunna, J Beyene… - …, 2023 - thelancet.com
Background Knowing the prevalence of multimorbidity among adults across continents is a
crucial piece of information for achieving Sustainable Development Goal 3.4, which calls for …

[HTML][HTML] Examining variation in the measurement of multimorbidity in research: a systematic review of 566 studies

ISS Ho, A Azcoaga-Lorenzo, A Akbari… - The Lancet Public …, 2021 - thelancet.com
Background A systematic understanding of how multimorbidity has been constructed and
measured is unavailable. This review aimed to examine the definition and measurement of …

[HTML][HTML] CODE-EHR best-practice framework for the use of structured electronic health-care records in clinical research

D Kotecha, FW Asselbergs, S Achenbach… - The Lancet Digital …, 2022 - thelancet.com
Big data is important to new developments in global clinical science that aim to improve the
lives of patients. Technological advances have led to the regular use of structured electronic …

[HTML][HTML] Self-rated health in individuals with and without disease is associated with multiple biomarkers representing multiple biological domains

L Kananen, L Enroth, J Raitanen, J Jylhävä, A Bürkle… - Scientific reports, 2021 - nature.com
Self-rated health (SRH) is one of the most frequently used indicators in health and social
research. Its robust association with mortality in very different populations implies that it is a …

[HTML][HTML] The role of oxidative stress in patients with recurrent pregnancy loss: a review

VA Zejnullahu, VA Zejnullahu, E Kosumi - Reproductive Health, 2021 - Springer
Background Recurrent pregnancy loss (RPL) presents one of the main problems in the field
of reproductive medicine, due to the unknown etiology in 50% of cases, as well as limited …

[HTML][HTML] AI and big data in healthcare: towards a more comprehensive research framework for multimorbidity

LT Majnarić, F Babič, S O'Sullivan… - Journal of Clinical …, 2021 - mdpi.com
Multimorbidity refers to the coexistence of two or more chronic diseases in one person.
Therefore, patients with multimorbidity have multiple and special care needs. However, in …

Cardiovascular outcomes and mortality associated with discontinuing statins in older patients receiving polypharmacy

F Rea, A Biffi, R Ronco, M Franchi… - JAMA network …, 2021 - jamanetwork.com
Importance Polypharmacy is a major health concern among older adults. While
deprescribing may reduce inappropriate medicine use, its effect on clinical end points …

Multimorbidity matters in low and middle-income countries

A Basto-Abreu, T Barrientos-Gutierrez… - Journal of …, 2022 - journals.sagepub.com
Multimorbidity is a complex challenge affecting individuals, families, caregivers, and health
systems worldwide. The burden of multimorbidity is remarkable in low-and middle-income …

[HTML][HTML] Organ system crosstalk in cardiometabolic disease in the age of multimorbidity

Y Oishi, I Manabe - Frontiers in cardiovascular medicine, 2020 - frontiersin.org
The close association among cardiovascular, metabolic, and kidney diseases suggests a
common pathological basis and significant interaction among these diseases. Metabolic …

[HTML][HTML] Multimorbidity and food insecurity in adults: a systematic review and meta-analysis

M Kantilafti, K Giannakou, S Chrysostomou - PLoS One, 2023 - journals.plos.org
Food insecurity is one of the main factors affecting multimorbidity. Previous studies have
shown that food insecurity may lead to multimorbidity due to person's inability to consume …