Free radicals are formed as a part of normal metabolic activities but are neutralized by the
endogenous antioxidants present in cells/tissue, thus maintaining the redox balance. This …

Spinal cord injury (SCI) triggers a complex cascade of molecular and chemical events that
leads to progressive cell loss and tissue damage. 1, 2 Nearly a century of fundamental basic …

After different types of acute central nervous system insults, including stroke, subarachnoid
haemorrhage and traumatic brain and spinal cord injuries, secondary damage plays a …

Mitochondria, with their intricate networks of functions and information processing, are
pivotal in both health regulation and disease progression. Particularly, mitochondrial …

This paper is an interdisciplinary narrative review of efficacious non-invasive therapies that
are increasingly used to restore function in people with chronic spinal cord injuries (SCI) …

Background: Insufficient neuronal mitochondrial bioenergetics supply occurs after spinal
cord injury (SCI), leading to neuronal apoptosis and impaired motor function. Previous …

Herein, we review evidence that targeting mitochondrial dysfunction with 'mitoceuticals' is an
effective neuroprotective strategy following neurotrauma, and that isolated exogenous …

Mitochondrial dysfunction occurs in the early stage of axonal degeneration after spinal cord
injury and involves oxidative stress, energy deficiency, imbalance of mitochondrial …

Bone cancer pain (BCP) is mainly caused by bone metastasis and markedly impairs the
functional capacity and daily functions of patients. Neuroinflammation plays a pivotal role in …

Mitochondrial transplantation provides a novel methodology for rescue of cell viability and
cell function following ischemia-reperfusion injury and applications for other pathologies are …