Importance Overt hyperthyroidism, defined assuppressed thyrotropin (previously thyroid-
stimulating hormone) and high concentration of triiodothyronine (T 3) and/or free thyroxine …

Hyperthyroidism is a common condition with a global prevalence of 0· 2–1· 3%. When
clinical suspicion of hyperthyroidism arises, it should be confirmed by biochemical tests (eg …

Nature achieves differentiation of specific and nonspecific binding in molecular interactions
through precise control of biomolecules in space and time. Artificial systems such as …

D-dimer is a soluble fibrin degradation product deriving from the plasmin-mediated
degradation of cross-linked fibrin. D-dimer can hence be considered a biomarker of …

Immunoassays are currently the methods of choice for the measurement of a large panel of
complex and heterogenous molecules owing to full automation, short turnaround time, high …

Immunoassays are powerful qualitative and quantitative analytical techniques. Since the first
description of an immunoassay method in 1959, advances have been made in assay …

Background: Despite being the most performed laboratory endocrine investigation, the
optimum use of thyroid tests (thyrotropin [TSH] and thyroid hormone [TH] measurement) is …

Hypothyroidism is the common clinical condition of thyroid hormone deficiency and, if left
untreated, can lead to serious adverse health effects on multiple organ systems, with the …

Drug Effects on the Thyroid The list of medications, many commonly used, that adversely
affect thyroid function or the interpretation of standard thyroid tests is growing. This review …

The hypothalamus-pituitary-thyroid axis is one of several hormone regulatory systems from
the hypothalamus to the pituitary and ultimately to the peripheral target organs. The …