Baculovirus: an insect-derived vector for diverse gene transfer applications
Insect-derived baculoviruses have emerged as versatile and safe workhorses of
biotechnology. Baculovirus expression vectors (BEVs) have been applied widely for crop …
biotechnology. Baculovirus expression vectors (BEVs) have been applied widely for crop …
Baculovirus as a tool for gene delivery and gene therapy
C Ono, T Okamoto, T Abe, Y Matsuura - Viruses, 2018 - mdpi.com
Based on its ability to express high levels of protein, baculovirus has been widely used for
recombinant protein production in insect cells for more than thirty years with continued …
recombinant protein production in insect cells for more than thirty years with continued …
Baculovirus as a gene delivery vector: recent understandings of molecular alterations in transduced cells and latest applications
Baculovirus infects insects in nature and is non-pathogenic to humans, but can transduce a
broad range of mammalian and avian cells. Thanks to the biosafety, large cloning capacity …
broad range of mammalian and avian cells. Thanks to the biosafety, large cloning capacity …
Solutions against emerging infectious and noninfectious human diseases through the application of baculovirus technologies
AM Targovnik, JA Simonin, GJ Mc Callum… - Applied microbiology …, 2021 - Springer
Baculoviruses are insect pathogens widely used as biotechnological tools in different fields
of life sciences and technologies. The particular biology of these entities (biosafety viruses 1; …
of life sciences and technologies. The particular biology of these entities (biosafety viruses 1; …
Baculovirus GP64-mediated entry into mammalian cells
C Kataoka, Y Kaname, S Taguwa, T Abe… - Journal of …, 2012 - Am Soc Microbiol
The baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) serves as
an efficient viral vector, not only for abundant gene expression in insect cells, but also for …
an efficient viral vector, not only for abundant gene expression in insect cells, but also for …
Baculovirus as vaccine vectors
S Madhan, M Prabakaran, J Kwang - Current gene therapy, 2010 - ingentaconnect.com
Application of viral vectors derived from human viruses to mediate immune response in
animals and humans has been greatly hampered by the problems associated with pre …
animals and humans has been greatly hampered by the problems associated with pre …
Residual baculovirus in insect cell-derived influenza virus-like particle preparations enhances immunogenicity
Influenza virus-like particles are currently evaluated in clinical trials as vaccine candidates
for influenza viruses. Most commonly they are produced in baculovirus-or mammalian …
for influenza viruses. Most commonly they are produced in baculovirus-or mammalian …
Baculoviruses in gene therapy and personalized medicine
This review will outline the role of baculoviruses in gene therapy and future potential in
personalized medicine. Baculoviruses are a safe, non-toxic, non-integrative vector with a …
personalized medicine. Baculoviruses are a safe, non-toxic, non-integrative vector with a …
Engineering of baculovirus vectors for the manufacture of virion‐free biopharmaceuticals
M Marek, MM van Oers, FF Devaraj… - Biotechnology and …, 2011 - Wiley Online Library
A novel baculovirus‐based protein expression strategy was developed to produce
recombinant proteins in insect cells without contaminating baculovirus virions. This novel …
recombinant proteins in insect cells without contaminating baculovirus virions. This novel …
Update on baculovirus as an expression and/or delivery vehicle for vaccine antigens
SY Lin, YC Chung, YC Hu - Expert review of vaccines, 2014 - Taylor & Francis
After three decades of development, the baculovirus/insect cell expression system is now
recognized as a powerful platform for recombinant protein production. With a number of …
recognized as a powerful platform for recombinant protein production. With a number of …