Breast cancer, the most frequently occurring cancer in women, is a major public health
problem, with 1,384,155 estimated new cases worldwide with nearly 459,000 related …

Through a comprehensive review and in silico analysis of reported data on STAT‐linked
diseases, we analysed the communication pathways and interactome of the seven STATs in …

Breast Cancer (BC) is a highly heterogeneous malignant carcinoma that is the most
frequently occurring cancer in women. The major types of BC are luminal A, basal-like …

Estrogen signaling is mediated by ERα and ERβ in hormone dependent, breast cancer (BC).
Over the last decade the implication of epigenetic pathways in BC tumorigenesis has …

Background: The 2010 guidelines by ASCO-CAP have mandated that breast cancer
specimens with≥ 1% positively staining cells by immunohistochemistry should be …

Epigenetic alterations are heritable changes in gene expression that occur without causing
any change in DNA sequence. They are important key factors for cancer development and …

Scope Reduced expression of tumor suppressor genes (TSG) increases the susceptibility to
breast cancer. However, only a small percentage of breast tumors is related to family history …

Epigenetic epidemiology includes the study of variation in epigenetic traits and the risk of
disease in populations. Its application to the field of cancer has provided insight into how …

Background Tumor expression of estrogen receptor (ER) is an important marker of
prognosis, and is predictive of response to endocrine therapy in breast cancer. Several …

The response to psychological stress can differ depending on the type and duration of the
stressor. Acute stress can facilitate a “fight or flight response” and aid survival, whereas …