Human age reversal: Fact or fiction?

AA Johnson, BW English, MN Shokhirev… - Aging …, 2022 - Wiley Online Library
Although chronological age correlates with various age‐related diseases and conditions, it
does not adequately reflect an individual's functional capacity, well‐being, or mortality risk …

[HTML][HTML] Stress, diet, exercise: Common environmental factors and their impact on epigenetic age

F Galkin, O Kovalchuk, D Koldasbayeva… - Ageing Research …, 2023 - Elsevier
Epigenetic aging clocks have gained significant attention as a tool for predicting age-related
health conditions in clinical and research settings. They have enabled geroscientists to …

Healthy lifestyle behaviors and biological aging in the US National Health and Nutrition Examination Surveys 1999–2018

A Thomas, DW Belsky, Y Gu - The Journals of Gerontology …, 2023 - academic.oup.com
People who have a balanced diet and engage in more physical activity live longer, healthier
lives. This study aimed to test the hypothesis that these associations reflect a slowing of …

Association between plant-based dietary pattern and biological aging trajectory in a large prospective cohort

S Wang, W Li, S Li, H Tu, J Jia, W Zhao, A Xu, W Xu… - BMC medicine, 2023 - Springer
Background Aging is a dynamic and heterogeneous process that may better be captured by
trajectories of aging biomarkers. Biological age has been advocated as a better biomarker of …

Essential nutrients, added sugar intake, and epigenetic age in midlife Black and White women: NIMHD Social Epigenomics Program

DT Chiu, EJ Hamlat, J Zhang, ES Epel… - JAMA Network …, 2024 - jamanetwork.com
Importance Nutritive compounds play critical roles in DNA replication, maintenance, and
repair, and also serve as antioxidant and anti-inflammatory agents. Sufficient dietary intakes …

[HTML][HTML] Composite dietary antioxidant index associated with delayed biological aging: a population-based study

H He, X Chen, Y Ding, X Chen, X He - Aging (Albany NY), 2024 - ncbi.nlm.nih.gov
Objective: The objective of this study was to explore the potential correlation between the
composite dietary antioxidant index (CDAI) and biological aging, addressing the insufficient …

Biomarkers of aging

Aging Biomarker Consortium, H Bao, J Cao… - Science China Life …, 2023 - Springer
Aging biomarkers are a combination of biological parameters to (i) assess age-related
changes,(ii) track the physiological aging process, and (iii) predict the transition into a …

Methylation-based biological age and hypertension prevalence and incidence

JK Kresovich, DP Sandler, JA Taylor - Hypertension, 2023 - Am Heart Assoc
Background: Hypertension is common in older individuals and is a major risk factor for
cardiovascular disease. Blood DNA methylation profiles have been used to derive metrics of …

The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial

A Yaskolka Meir, M Keller, A Hoffmann, E Rinott… - BMC medicine, 2023 - Springer
Background Epigenetic age is an estimator of biological age based on DNA methylation; its
discrepancy from chronologic age warrants further investigation. We recently reported that …

[HTML][HTML] Air pollution and epigenetic aging among Black and White women in the US

SH Koenigsberg, CJ Chang, J Ish, Z Xu… - Environment …, 2023 - Elsevier
Background DNA methylation-based measures of biological aging have been associated
with air pollution and may link pollutant exposures to aging-related health outcomes …