G-quadruplexes in cancer-related gene promoters: from identification to therapeutic targeting
F Romano, A Di Porzio, N Iaccarino… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction Guanine-rich DNA sequences can fold into four-stranded noncanonical
secondary structures called G-quadruplexes (G4s) which are widely distributed in functional …
secondary structures called G-quadruplexes (G4s) which are widely distributed in functional …
Good Vibrations Report on the DNA Quadruplex Binding of an Excited State Amplified Ruthenium Polypyridyl IR Probe
M Stitch, D Avagliano, D Graczyk, IP Clark… - Journal of the …, 2023 - ACS Publications
The nitrile containing Ru (II) polypyridyl complex [Ru (phen) 2 (11, 12-dCN-dppz)] 2+(1) is
shown to act as a sensitive infrared probe of G-quadruplex (G4) structures. UV–visible …
shown to act as a sensitive infrared probe of G-quadruplex (G4) structures. UV–visible …
Metal centers and aromatic moieties in Schiff base complexes: impact on G-quadruplex stabilization and oncogene downregulation
A Froux, L D'Anna, A Rainot, C Neybecker… - Inorganic Chemistry …, 2024 - pubs.rsc.org
We present the synthesis and characterization of novel square planar transition metal
complexes of Schiff base ligands, which act as guanine quadruplex binders and stabilizers …
complexes of Schiff base ligands, which act as guanine quadruplex binders and stabilizers …
Alloxazine-Based Ligands and Their Ruthenium Complexes as NADH Oxidation Catalysts and G4 Binders
MJ Móran Plata, L Marretta, L Gaztelumendi… - Inorganic …, 2024 - ACS Publications
Flavin-like ligands (L-1 and L-2) with extended π-conjugation were synthesized using
microwave-assisted techniques. An N, N-chelating fragment was integrated into alloxazine …
microwave-assisted techniques. An N, N-chelating fragment was integrated into alloxazine …
In Silico Design of a Solution-Gated Graphene Transistor Sensor for the Efficient Detection of Guanine Quadruplexes
Guanine quadruplexes (G4s) are nucleic acid structures present in diverse regions of the
genome, such as telomeres and transcription initiators. Recently, the different biological …
genome, such as telomeres and transcription initiators. Recently, the different biological …
Alloxazine-Based Ligands And Their Ruthenium Complexes As NADH Oxidation Catalysts And G4 Binders
MJM Plata, L Marretta, L Gaztelumendi, GE Pieslinger… - 2024 - chemrxiv.org
Flavin-like ligands (L-1 and L-2) with extended π-conjugation were synthesized using
microwave-assisted techniques. An N, N-chelating fragment was integrated into alloxazine …
microwave-assisted techniques. An N, N-chelating fragment was integrated into alloxazine …