Cervical cancer develops from well‐defined precursor lesions referred to as either cervical
intraepithelial neoplasia or squamous intraepithelial lesions. It is now known that specific …

Both cytogenetic and molecular genetic approaches have unveiled non‐random genomic
alterations in Ip associated with a number of human malignancies. These have been …

It has been shown that the Hdmx gene is amplified in a subset of gliomas, but thus far, no
data are available on HDMX protein expression in tumor cells. We now report that a …

Abstract The p16 (MTS1) tumour-suppressor gene is a cyclin-dependent kinase (cdk)
inhibitor that decelerates the cell cycle by inactivating the cdks that phosphorylate the …

Three undifferentiated nasopharyngeal carcinoma (NPC) tumour lines were successfully
established from fresh biopsy material injected sc into athymic mice and passaged for many …

Recently, two homologous genes, EXT1 and EXT2, with a putative tumor suppressor
function have been described. Mutations in both genes are responsible for multiple …

Cytogenetic studies on carcinoma of the cervix have shown the nonrandom involvement in
structural changes of a number of chromosomes, particularly chromosomes 1, 3, 5, 11, and …

Cervical cancer develops from precancerous high-grade cervical intraepithelial neoplasia
(CIN) harboring a transforming infection with high-risk human papillomavirus, which is …

OBJECTIVE: To determine, through the micronucleus (MN) test, the cytogenetic effects of
cigarette smoking on exfoliated cells from the uterine cervix in women with normal smears …

A summary of the chromosome changes in 43 carcinomas of the cervix studied by a direct
technique showed that the most common anomaly was a small metacentric [in 77%, often in …