Colorectal cancer through simulation and experiment

SK Kershaw, HM Byrne, DJ Gavaghan… - IET systems …, 2013 - Wiley Online Library
Colorectal cancer (CRC) has formed a canonical example of tumourigenesis ever since its
use in Fearon and Vogelstein's linear model of genetic mutation, and continues to generate …

A convection-diffusion-shape model for aberrant colonic crypt morphogenesis

IN Figueiredo, C Leal, G Romanazzi, B Engquist… - … and Visualization in …, 2011 - Springer
It is generally accepted that colorectal cancer is initiated in the small pits, called crypts, that
line the colon. Normal crypts exhibit a regular pit pattern, similar in two-dimensions to a U …

Homogenization model for aberrant crypt foci

IN Figueiredo, C Leal, G Romanazzi, B Engquist - SIAM Journal on Applied …, 2016 - SIAM
Several explanations can be found in the literature about the origin of colorectal cancer.
There is, however, some agreement on the fact that the carcinogenic process is a result of …

A multiscale model for aberrant crypt foci

IN Figueiredo, G Romanazzi, C Leal… - Procedia Computer …, 2013 - Elsevier
Computational models of cancer complement the biological study of tumor growth. However,
existing modeling approaches can be both inefficient and inaccurate due to the difficulties of …

[PDF][PDF] A numerical simulation for aberrant crypt foci

G Romanazzi, IN Figueiredo… - Proceedings of 10th World …, 2012 - pdf.blucher.com.br
It is generally accepted that colorectal cancer (CRC) occurs as a consequence of several
genetic mutations in the colonic mucosa. The detection and assessment of aberrant crypt …

[PDF][PDF] PARAMETER RELEVANCE IN A THREE DIMENSIONAL COLONIC CRYPT MODEL

IN Figueiredo, C Leal, G Romanazzi - congress.cimne.com
Colorectal cancer is one of the most frequent type of cancer in the western world [1].
Different scientific communities have studied its morphogenesis from geneticists to …

Segmentation of Aberrant Crypt Foci using Computational Vision

LF da Silva Ribeiro - 2013 - search.proquest.com
Colorectal cancer is a type of cancer that develops in the large intestine (colon) or the
rectum. As it affects both these areas it called colorectal cancer, one of the most common …

[PDF][PDF] Report Number 12/29

SK Kershaw, HM Byrne, DJ Gavaghan, JM Osborne - core.ac.uk
Colorectal cancer has continued to generate a huge amount of research interest over
several decades, forming a canonical example of tumourigenesis since its use in Fearon …

A Numerical Simulation for Aberrant Crypt Foci

IN Figueiredo, C Leal - Blucher Mechanical …, 2012 - proceedings.blucher.com.br
It is generally accepted that colorectal cancer (CRC) occurs as a consequence of several
genetic mutations in the colonic mucosa. The detection and assessment of aberrant crypt …

[PS][PS] Isabel N. Figueiredo CMUC, Department of Mathematics, University of Coimbra, 3001-454 Coimbra, Portugal E-mail address: isabelf@ mat. uc. pt

C Leal, G Romanazzi - growth, 2007 - mat.uc.pt
It is generally accepted that colorectal cancer is initiated in the small pits, called crypts, that
line the colon. Normal crypts exhibit a regular pit pattern, similar in two-dimensions to a U …