Bioinspired yeast-based β-glucan system for oral drug delivery

Y Wu, P Li, Z Jiang, X Sun, H He, P Yan, Y Xu… - Carbohydrate …, 2023 - Elsevier
Oral drug delivery is the preferred route of drug administration for patients, especially those
who need long-term medication. Recently, bioinspired drug delivery systems have emerged …

Exploring probiotic effector molecules and their mode of action in gut–immune interactions

CG Lee, KH Cha, GC Kim, SH Im… - FEMS Microbiology …, 2023 - academic.oup.com
Probiotics, live microorganisms that confer health benefits when consumed in adequate
amounts, have gained significant attention for their potential therapeutic applications. The …

Twin-bioengine self-adaptive micro/nanorobots using enzyme actuation and macrophage relay for gastrointestinal inflammation therapy

B Zhang, H Pan, Z Chen, T Yin, M Zheng, L Cai - Science Advances, 2023 - science.org
A wide array of biocompatible micro/nanorobots are designed for targeted drug delivery and
precision therapy largely depending on their self-adaptive ability overcoming complex …

Macrophage‐hitchhiked orally administered β‐glucans‐functionalized nanoparticles as “precision‐guided stealth missiles” for targeted pancreatic cancer therapy

KH Chen, N Nguyen, TY Huang, YJ Lin… - Advanced …, 2023 - Wiley Online Library
The prognosis in cases of pancreatic ductal adenocarcinoma (PDAC) with current treatment
modalities is poor owing to the highly desmoplastic tumor microenvironment (TME). Herein …

pH‐Responsive β‐Glucans‐Complexed mRNA in LNPs as an Oral Vaccine for Enhancing Cancer Immunotherapy

PK Luo, HM Ho, MC Chiang, LA Chu… - Advanced …, 2024 - Wiley Online Library
Abstract mRNA vaccines for cancer immunotherapy are commonly delivered using lipid
nanoparticles (LNPs), which, when administered intravenously, may accumulate in the liver …

β-glucans: a potential source for maintaining gut microbiota and the immune system

RP Singh, A Bhardwaj - Frontiers in Nutrition, 2023 - frontiersin.org
The human gastrointestinal (GI) tract holds a complex and dynamic population of microbial
communities, which exerts a marked influence on the host physiology during homeostasis …

[HTML][HTML] An important polysaccharide from fermentum

B Lin, G Huang - Food Chemistry: X, 2022 - Elsevier
Fermentum is a common unicellular fungus with many biological activities attributed to β-
polysaccharides. Different in vivo and in vivo experimental studies have long proven that …

α-D-1, 6-glucan from Castanea mollissima Blume alleviates dextran sulfate sodium-induced colitis in vivo

H Li, W Cao, J Xie, H Che, L Liu, X Dong, L Song… - Carbohydrate …, 2022 - Elsevier
Abstract A homogenous α-D-1, 6-glucan (CPA) was extracted from Castanea mollissima
Blume. The effect of CPA on ameliorating dextran sulfate sodium induced colitis was …

Yeast β-glucan attenuates dextran sulfate sodium-induced colitis: Involvement of gut microbiota and short-chain fatty acids

S Li, H Peng, Y Sun, J Yang, J Wang, F Bai… - International Journal of …, 2024 - Elsevier
Yeast β-glucan intervention offers a promising strategy for managing colitis; however, the
mechanisms remain unknown. In the present work, the protective effects of yeast β-glucan …

Myeloid C-type lectin receptors in innate immune recognition

CR e Sousa, S Yamasaki, GD Brown - Immunity, 2024 - cell.com
C-type lectin receptors (CLRs) expressed by myeloid cells constitute a versatile family of
receptors that play a key role in innate immune recognition. Myeloid CLRs exhibit a …