Added value of chromosomal microarray analysis over karyotyping in early pregnancy loss: systematic review and meta‐analysis

M Pauta, M Grande… - … in Obstetrics & …, 2018 - Wiley Online Library
Objective To estimate the increased test success rate and incremental yield of chromosomal
microarray analysis (CMA) over conventional karyotyping in detection of pathogenic copy …

Overview of chromosome abnormalities in first trimester miscarriages: a series of 1,011 consecutive chorionic villi sample karyotypes

A Soler, C Morales, I Mademont-Soler… - … and genome research, 2017 - karger.com
In order to contribute to the knowledge of type and frequency of chromosome abnormalities
in early pregnancy losses, we analyzed the cytogenetic results from a large series of first …

Genetic causes of sporadic and recurrent miscarriage

P Melo, R Dhillon-Smith, MA Islam, A Devall… - Fertility and …, 2023 - Elsevier
Approximately 80% of miscarriages happen within the first 12 weeks of gestation. More than
half of early losses result from genetic defects, usually presenting as abnormal chromosome …

Maternal age, history of miscarriage, and embryonic/fetal size are associated with cytogenetic results of spontaneous early miscarriages

N Ozawa, K Ogawa, A Sasaki, M Mitsui, S Wada… - Journal of assisted …, 2019 - Springer
Purpose To clarify the associations of the maternal age, history of miscarriage, and
embryonic/fetal size at miscarriage with the frequencies and profiles of cytogenetic …

The effect of maternal age on chromosomal anomaly rate and spectrum in recurrent miscarriage

M Grande, A Borrell, R Garcia-Posada… - Human …, 2012 - academic.oup.com
STUDY QUESTION Is there any effect of maternal age on chromosomal anomaly rate and
spectrum in recurrent miscarriage? SUMMARY ANSWER There was no significant …

Chromosomal aneuploidy associated with clinical characteristics of pregnancy loss

C Gu, K Li, R Li, L Li, X Li, X Dai, Y He - Frontiers in Genetics, 2021 - frontiersin.org
Objective Embryonic aneuploidy is found in about half of sporadic pregnancy losses and the
associations between the chromosomal aneuploidy and clinical characteristics of pregnancy …

Whole‑exome sequencing analysis of products of conception identifies novel mutations associated with missed abortion

M Fu, S Mu, C Wen, S Jiang, L Li… - Molecular …, 2018 - spandidos-publications.com
Missed abortion (MA) refers to a pregnancy in which there is fetal demise without outside
intervention, and additionally no uterine activity that may expel the product of conception …

Miscarriage in contemporary maternal-fetal medicine: targeting clinical dilemmas.

A Borrell, I Stergiotou - Ultrasound in Obstetrics & …, 2013 - search.ebscohost.com
The article presents the author's views on miscarriage in contemporary maternal-fetal
medicine. He describes the factors responsible for miscarriage, and challenges faced by …

Chromosome distribution of early miscarriages with present or absent embryos: female predominance

HH Cheng, CY Ou, CC Tsai, SD Chang… - Journal of assisted …, 2014 - Springer
Purpose The objective of this study is to compare the chromosomal distribution of early
miscarriages with or without embryonic poles. Materials and methods It was a retrospective …

[HTML][HTML] Role of ovarian reserve markers, antimüllerian hormone and antral follicle count, as aneuploidy markers in ongoing pregnancies and miscarriages

M Grande, V Borobio, M Bennasar, I Stergiotou… - Fertility and sterility, 2015 - Elsevier
Objective To assess the role of two ovarian reserve markers, antimüllerian hormone (AMH)
and antral follicle count (AFC), as markers of the background risk for fetal trisomy. Design …