Breast cancer develops in the mammary glands during mammalian adulthood and is
considered the second most common type of human carcinoma and the most incident and …

HOX family transcription factors belong to a highly conserved subgroup of the homeobox
superfamily that determines cellular fates in embryonic morphogenesis and the …

DNA in cells is predominantly B-form double helix. Though certain DNA sequences in vitro
may fold into other structures, such as triplex, left-handed Z form, or quadruplex DNA, the …

Despite a generally better prognosis than high-grade glioma (HGG), recurrence and
malignant progression are the main causes for the poor prognosis and difficulties in the …

Homeobox (HOX) genes encode highly conserved homeotic transcription factors that play a
crucial role in organogenesis and tissue homeostasis. Their deregulation impacts the …

HOXA1, a member of the HOX gene family, has been implicated in tumor progression.
However, the role of HOXA1 in prostate cancer is not well-established. In the present study …

The human histamine receptor H1 (HRH1) gene is located on chromosome 3p25 and
encodes for a 487 amino acid G protein-coupled receptor (GPCR) with a long third …

Emerging evidence has shown that microRNAs (miRNAs) play important roles in tumor
development and progression. In particular, miR-30b is thought to be closely related to the …

More than 25 years ago, the first literature records mentioned HOXA1 expression in human
breast cancer. A few years later, HOXA1 was confirmed as a proper oncogene in mammary …

Although prolactin (PRL) and its receptor (PRLR) have been detected in glioblastoma
multiforme (GBM), their role in its pathogenesis remains unclear. Our aim was to explore …