Ischemic stroke is a sudden loss of brain function due to the reduction of blood flow. Brain
tissues cease to function with subsequent activation of the ischemic cascade. Metabolomics …

Introduction: Studying changes in the whole set of small molecules, final products of
biochemical reactions in living systems or metabolites, is extremely appealing because they …

Ischemic stroke is a serious public health problem worldwide. Here, we characterized the
metabolite features of acute ischemic stroke (AIS) using a gas chromatography-mass …

Introduction Obstructive sleep apnea (OSA) is a chronic, heterogeneous and
multicomponent disorder with associated cardiovascular and metabolic alterations. Despite …

Stroke is a major reason for disability and the second highest cause of death in the world.
When a patient is admitted to a hospital, it is necessary to identify the type of stroke, and the …

Metabolic dysfunction impacts stroke incidence and outcome. However, the intricate
association between altered metabolic program due to aging, and focal ischemia in brain …

Human phenomics is defined as the comprehensive collection of observable phenotypes
and characteristics influenced by a complex interplay among factors at multiple scales …

Background Stroke burden is extremely high in Chinese hypertensive population. Novel
biomarkers for cardiovascular diseases can be detected by metabolomic profiling of human …

A non-dipping blood pressure (BP) pattern, which is frequently present in patients with
obstructive sleep apnea (OSA), confers high cardiovascular risk. The mechanisms …

Transient ischemic attacks (TIAs) before an acute ischemic stroke (AIS) could induce
ischemic tolerance (IT) phenomena. with an endogenous neuroprotective role (Ischemic …