From bed to bench and back: TNF-α, IL-23/IL-17A, and JAK-dependent inflammation in the pathogenesis of psoriatic synovitis
Psoriatic arthritis (PsA) is a chronic inflammatory immune-mediated disease with a
burdensome impact on quality of life and substantial healthcare costs. To date …
burdensome impact on quality of life and substantial healthcare costs. To date …
[HTML][HTML] Exploring the causal relationship between inflammatory cytokines and inflammatory arthritis: A Mendelian randomization study
S Pan, S Wu, Y Wei, J Liu, C Zhou, T Chen, J Zhu… - Cytokine, 2024 - Elsevier
Objectives Previous studies have reported an association between inflammatory cytokines
and inflammatory arthritis, including Ankylosing spondylitis (AS), rheumatoid arthritis (RA) …
and inflammatory arthritis, including Ankylosing spondylitis (AS), rheumatoid arthritis (RA) …
Evaluation of the synovial effects of biological and targeted synthetic DMARDs in patients with psoriatic arthritis: A systematic literature review and meta-analysis
MS Ciliento, V Venturelli, N Schettini, R Bertola… - International Journal of …, 2023 - mdpi.com
The aims of this systematic literature review (SLR) were to identify the effects of approved
biological and targeted synthetic disease modifying antirheumatic drugs (b/tsDMARDs) on …
biological and targeted synthetic disease modifying antirheumatic drugs (b/tsDMARDs) on …
High-grade synovitis associates with clinical markers and response to therapy in chronic inflammatory arthritis: post hoc analysis of a synovial biomarkers prospective …
C Garaffoni, M Tamussin, I Calciolari, G Lanza… - Frontiers in …, 2024 - frontiersin.org
Background Inflammatory arthritis (IAs), such as rheumatoid arthritis (RA) and psoriatic
arthritis (PsA), are characterized by the presence of chronic synovitis. The Krenn's synovitis …
arthritis (PsA), are characterized by the presence of chronic synovitis. The Krenn's synovitis …
Эффективность и безопасность тофацитиниба при иммуновоспалительных ревматических заболеваниях (часть I)
ЕЛ Насонов, АС Авдеева, АМ Лила - Научно-практическая …, 2020 - cyberleninka.ru
Расшифровка механизмов патогенеза иммуновоспалительных ревматических
заболеваний (ИВРЗ) в сочетании с разработкой широкого спектра генно-инженерных …
заболеваний (ИВРЗ) в сочетании с разработкой широкого спектра генно-инженерных …
[HTML][HTML] Tofacitinib restores psoriatic arthritis fibroblast-like synoviocytes function via autophagy and mitochondrial quality control modulation
Objectives To evaluate the in vitro effect of tofacitinib on autophagy activity of psoriatic
arthritis (PsA) fibroblast-like synoviocytes (FLS), and to confirm its activity on inflammatory …
arthritis (PsA) fibroblast-like synoviocytes (FLS), and to confirm its activity on inflammatory …
In vitro-in silico evaluation of Apremilast solid dispersions prepared via Corotating Twin Screw Extruder
A Muvva, D Lakshman, VSNM Dwibhashyam… - Journal of Drug Delivery …, 2020 - Elsevier
The purpose of this study was to employ the Hot melt extrusion technique (HME) to prepare
amorphous solid dispersions (ASDs) of Apremilast, a BCS class IV drug. Drug–polymer …
amorphous solid dispersions (ASDs) of Apremilast, a BCS class IV drug. Drug–polymer …
Research progress in drug therapy of juvenile idiopathic arthritis
WJ Zhao, JH Deng, CF Li - World Journal of Pediatrics, 2022 - Springer
Background Juvenile idiopathic arthritis (JIA) is the most common chronic rheumatic disease
in children. With the gradual expansion of the incidence of JIA in the population, the …
in children. With the gradual expansion of the incidence of JIA in the population, the …
German mobile apps for patients with psoriatic arthritis: systematic app search and content analysis
G Gross, C Lull, J von Ahnen, V Olsavszky… - Health Policy and …, 2022 - Elsevier
Abstract Background Psoriatic arthritis (PsA) is a chronic musculoskeletal disease.
Functional limitations result in significant patient burden. The use of smartphone apps to …
Functional limitations result in significant patient burden. The use of smartphone apps to …
Higher Synovial Immunohistochemistry Reactivity of IL-17A, Dkk1, and TGF-β1 in Patients with Early Psoriatic Arthritis and Rheumatoid Arthritis Could Predict the Use …
JA Pinto-Tasende, M Fernandez-Moreno, I Rego Perez… - Biomedicines, 2024 - mdpi.com
Background: Delay in diagnosis and therapy in patients with arthritis commonly leads to
progressive articular damage. The study aimed to investigate the immunohistochemical …
progressive articular damage. The study aimed to investigate the immunohistochemical …