Targeted drug delivery in cancer typically focuses on maximising the endocytosis of drugs
into the diseased cells. However, there has been less focus on exploiting the differences in …

The greatest obstacle to using drugs to treat brain tumors is the blood‐brain barrier (BBB),
making it difficult for conventional drug molecules to enter the brain. Therefore, how to safely …

The intracellular pH (pHi) in organelles, including mitochondria, endoplasmic reticulum,
lysosomes, and nuclei, differs from the cytoplasmic pH, and thus maintaining the pH of these …

The success of gene therapy relies on gene nanocarriers to achieve therapeutic effects in
vivo. Surface shielding of poly (ethylene glycol)(PEG), known as PEGylation, onto gene …

Tumor hypoxia poses a significant challenge in photodynamic therapy (PDT), which uses
molecular oxygen to produce reactive oxygen species upon light excitation of a …

Intracellular protein delivery is a powerful strategy for developing innovative therapeutics.
Nanocarriers present great potential to deliver proteins inside cells by promoting cellular …

Developing drug delivery carriers for highly selective, controlled, and sustained release of
the anti-cancer drugs is one of the crucial issues in the cancer strive. We herein report the …

Curing cancer has drastically improved in recent decades, but it is essential to find more
effective and specific treatments. Radiotherapy and chemotherapy can cause serious side …

Functional fluorophores represent an emerging research field, distinguished by their diverse
applications, especially in sensing and cellular imaging. After the discovery of quinine …

Chitosan-functionalized magnetite/poly (ε-caprolactone) nanoparticles were formulated by
interfacial polymer disposition plus coacervation, and loaded with gemcitabine. That …