[HTML][HTML] Biological subtypes of breast cancer: Prognostic and therapeutic implications

O Yersal, S Barutca - World journal of clinical oncology, 2014 - ncbi.nlm.nih.gov
Breast cancer is a heterogeneous complex of diseases, a spectrum of many subtypes with
distinct biological features that lead to differences in response patterns to various treatment …

Luminal B breast cancer: molecular characterization, clinical management, and future perspectives

F Ades, D Zardavas, I Bozovic-Spasojevic… - Journal of clinical …, 2014 - ascopubs.org
Gene expression profiling has reshaped our understanding of breast cancer by defining and
characterizing four main intrinsic molecular subtypes: human epidermal growth factor …

[HTML][HTML] Meta-analysis of the association of breast cancer subtype and pathologic complete response to neoadjuvant chemotherapy

N Houssami, P Macaskill, G von Minckwitz… - European journal of …, 2012 - Elsevier
BACKGROUND: Pathologic complete response (pCR) is a surrogate end-point for prognosis
in neoadjuvant chemotherapy (NAC) for breast cancer. We aimed to report summary …

Tumour-infiltrating CD8+ lymphocytes as an independent predictive factor for pathological complete response to primary systemic therapy in breast cancer

AN Seo, HJ Lee, EJ Kim, HJ Kim, MH Jang… - British journal of …, 2013 - nature.com
Background: Tumour-infiltrating lymphocytes (TILs) are known to be associated with
response to primary systemic therapy (PST) in breast cancer. This study was conducted to …

Ki67, chemotherapy response, and prognosis in breast cancer patients receiving neoadjuvant treatment

PA Fasching, K Heusinger, L Haeberle, M Niklos… - BMC cancer, 2011 - Springer
Background The pathological complete response (pCR) after neoadjuvant chemotherapy is
a surrogate marker for a favorable prognosis in breast cancer patients. Factors capable of …

Luminal-B breast cancer and novel therapeutic targets

B Tran, PL Bedard - Breast Cancer Research, 2011 - Springer
Gene expression profiling has led to a new molecular classification of breast cancer
characterized by four intrinsic subtypes: basal-like, HER2-positive, luminal A, and luminal B …

The value of tumor infiltrating lymphocytes (TILs) for predicting response to neoadjuvant chemotherapy in breast cancer: a systematic review and meta-analysis

Y Mao, Q Qu, Y Zhang, J Liu, X Chen, K Shen - PloS one, 2014 - journals.plos.org
Background We carried out a systematic review and meta-analysis to evaluate the predictive
roles of tumor infiltrating lymphocytes (TILs) in response to neoadjuvant chemotherapy …

[HTML][HTML] Chemotherapy (CT) and hormonotherapy (HT) as neoadjuvant treatment in luminal breast cancer patients: results from the GEICAM/2006-03, a multicenter …

E Alba, L Calvo, J Albanell, JR De la Haba, AA Lanza… - Annals of oncology, 2012 - Elsevier
Background Luminal breast cancer is a highly endocrine responsive disease. However, the
therapeutic benefit of chemotherapy (CT) in this population is not fully characterized. This …

Neoadjuvant chemotherapy in breast cancers

S Masood - Women's Health, 2016 - journals.sagepub.com
With advances in science and technology, there are more innovations in the approach to
management of patients with breast cancer. Neoadjuvant chemotherapy that is designed to …

An increase in cancer stem cell population after primary systemic therapy is a poor prognostic factor in breast cancer

HE Lee, JH Kim, YJ Kim, SY Choi, SW Kim… - British journal of …, 2011 - nature.com
Background: The cancer stem cell (CSC) hypothesis has important clinical implications for
cancer therapeutics because of the proposed role of CSCs in chemoresistance. The aim of …