Acetylcholinesterase inhibitors in the treatment of neurodegenerative diseases and the role of acetylcholinesterase in their pathogenesis

ŁJ Walczak-Nowicka, M Herbet - International journal of molecular …, 2021 - mdpi.com
Acetylcholinesterase (AChE) plays an important role in the pathogenesis of
neurodegenerative diseases by influencing the inflammatory response, apoptosis, oxidative …

The Nrf2/HO‐1 Axis as targets for flavanones: Neuroprotection by pinocembrin, naringenin, and Eriodictyol

S Habtemariam - Oxidative medicine and cellular longevity, 2019 - Wiley Online Library
Flavanones are a group of flavonoids that derive from their immediate chalcone precursors
through the action of chalcone isomerase enzymes. The Aromatic A and B rings, C4‐keto …

Naringenin: A prospective therapeutic agent for Alzheimer's and Parkinson's disease

A Goyal, A Verma, N Dubey, J Raghav… - Journal of Food …, 2022 - Wiley Online Library
Neurodegenerative disorders (NDs) are a cluster of progressive, severe, and disabling
disorders that affect millions of people worldwide and are on the surge. These disorders are …

Potential therapeutic use of plant flavonoids in AD and PD

S Meng-Zhen, L Ju, Z Lan-Chun, D Cai-Feng… - Heliyon, 2022 - cell.com
Background Millions of people suffer from Alzheimer's disease (AD) and Parkinson's
disease (PD) worldwide. Due to their complex pathology, no effective pharmacological …

Natural Anti-inflammatory compounds as Drug candidates in Alzheimer's disease

RH Mir, AJ Shah, R Mohi-Ud-Din… - Current medicinal …, 2021 - benthamdirect.com
Alzheimer's disease (AD) is a chronic neurodegenerative brain disorder characterized by
memory impairment, dementia, and oxidative stress in elderly people. Currently, only a few …

The neuroprotective mechanisms of naringenin: Inhibition of apoptosis through the PI3K/AKT pathway after hypoxic-ischemic brain damage

L Li, Z Lin, J Yuan, P Li, Q Wang, N Cho… - Journal of …, 2024 - Elsevier
Ethnopharmacological relevance Naringenin (NGN) is a widely distributed flavonoid with
potent antioxidant and neuroprotective properties. Neuroprotective agents play a crucial role …

Role of flavonoids in neurodegenerative diseases: limitations and future perspectives

G Maan, B Sikdar, A Kumar, R Shukla… - Current Topics in …, 2020 - ingentaconnect.com
Background: Flavonoids, a group of natural dietary polyphenols, are known for their
beneficial effects on human health. By virtue of their various pharmacological effects, like …

Effects of flavonoids on cancer, cardiovascular and neurodegenerative diseases: Role of NF-κB signaling pathway

MM Barreca, R Alessandro, C Corrado - International Journal of …, 2023 - mdpi.com
Flavonoids are polyphenolic phytochemical compounds found in many plants, fruits,
vegetables, and leaves. They have a multitude of medicinal applications due to their anti …

Non-enzymatic antioxidants against Alzheimer's disease: prevention, diagnosis and therapy

A Varesi, LIM Campagnoli, A Carrara, I Pola, E Floris… - Antioxidants, 2023 - mdpi.com
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive
memory loss and cognitive decline. Although substantial research has been conducted to …

Naringenin Upregulates AMPK-Mediated Autophagy to Rescue Neuronal Cells From β-Amyloid (1–42) Evoked Neurotoxicity

AU Ahsan, VL Sharma, A Wani, M Chopra - Molecular Neurobiology, 2020 - Springer
Deposition of an amyloid-β peptide is one of the first events in the pathophysiology of
Alzheimer's disease (AD) and is clinically characterized by Aβ plaques, tau tangles, and …