A narrative review of molecular mechanism and therapeutic effect of cannabidiol (CBD)

J Peng, M Fan, C An, F Ni, W Huang… - Basic & clinical …, 2022 - Wiley Online Library
Cannabidiol (CBD) is an abundant non‐psychoactive phytocannabinoid in cannabis
extracts which has high affinity on a series of receptors, including Type 1 cannabinoid …

Antioxidative and anti-inflammatory properties of cannabidiol

S Atalay, I Jarocka-Karpowicz, E Skrzydlewska - Antioxidants, 2019 - mdpi.com
Cannabidiol (CBD) is one of the main pharmacologically active phytocannabinoids of
Cannabis sativa L. CBD is non-psychoactive but exerts a number of beneficial …

Therapeutic potential of cannabis, cannabidiol, and cannabinoid-based pharmaceuticals

CA Legare, WM Raup-Konsavage, KE Vrana - Pharmacology, 2022 - karger.com
Background: There is a growing interest in the use of cannabis (and its extracts), as well as
CBD oil (hemp extracts containing cannabidiol), for therapeutic purposes. While there is …

Phytocannabinoids: a unified critical inventory

LO Hanuš, SM Meyer, E Muñoz… - Natural product …, 2016 - pubs.rsc.org
Covering up to January 2016 Cannabis sativa L. is a prolific, but not exclusive, producer of a
diverse group of isoprenylated resorcinyl polyketides collectively known as …

Cannabidiol for pain treatment: focus on pharmacology and mechanism of action

J Mlost, M Bryk, K Starowicz - International journal of molecular sciences, 2020 - mdpi.com
Cannabis has a long history of medical use. Although there are many cannabinoids present
in cannabis, Δ9tetrahydrocannabinol (Δ9-THC) and cannabidiol (CBD) are the two …

Molecular targets of the phytocannabinoids: a complex picture

P Morales, DP Hurst, PH Reggio - Phytocannabinoids: Unraveling the …, 2017 - Springer
For centuries, hashish and marihuana, both derived from the Indian hemp Cannabis sativa
L., have been used for their medicinal, as well as, their psychotropic effects. These effects …

In vitro and in vivo pharmacological activity of minor cannabinoids isolated from Cannabis sativa

A Zagzoog, KA Mohamed, HJJ Kim, ED Kim… - Scientific Reports, 2020 - nature.com
The Cannabis sativa plant contains more than 120 cannabinoids. With the exceptions of∆ 9-
tetrahydrocannabinol (∆ 9-THC) and cannabidiol (CBD), comparatively little is known about …

An update on PPAR activation by cannabinoids

SE O'Sullivan - British journal of pharmacology, 2016 - Wiley Online Library
Some cannabinoids activate the different isoforms of PPARs (α, β and γ), as shown through
the use of reporter gene assays, binding studies, selective antagonists and knockout …

The Effects of Cannabinoids on Pro- and Anti-Inflammatory Cytokines: A Systematic Review of In Vivo Studies

FR Henshaw, LS Dewsbury, CK Lim… - Cannabis and …, 2021 - liebertpub.com
Introduction: Some cannabinoids have been identified as anti-inflammatory agents;
however, their potential therapeutic or prophylactic applications remain controversial. The …

The origin and biomedical relevance of cannabigerol

A Jastrząb, I Jarocka-Karpowicz… - International journal of …, 2022 - mdpi.com
The constant search for new pharmacologically active compounds, especially those that do
not exhibit toxic effects, intensifies the interest in plant-based ingredients and their potential …