Multiscale change point inference

K Frick, A Munk, H Sieling - … the Royal Statistical Society Series B …, 2014 - academic.oup.com
We introduce a new estimator, the simultaneous multiscale change point estimator SMUCE,
for the change point problem in exponential family regression. An unknown step function is …

The SARS-CoV-2 accessory protein Orf3a is not an ion channel, but does interact with trafficking proteins

AN Miller, PR Houlihan, E Matamala… - Elife, 2023 - elifesciences.org
The severe acute respiratory syndrome associated coronavirus 2 (SARS-CoV-2) and SARS-
CoV-1 accessory protein Orf3a colocalizes with markers of the plasma membrane, endocytic …

Changepoint detection in the presence of outliers

P Fearnhead, G Rigaill - Journal of the American Statistical …, 2019 - Taylor & Francis
Many traditional methods for identifying changepoints can struggle in the presence of
outliers, or when the noise is heavy-tailed. Often they will infer additional changepoints to fit …

Seeded binary segmentation: a general methodology for fast and optimal changepoint detection

S Kovács, P Bühlmann, H Li, A Munk - Biometrika, 2023 - academic.oup.com
We propose seeded binary segmentation for large-scale changepoint detection problems.
We construct a deterministic set of background intervals, called seeded intervals, in which …

Hrd1 forms the retrotranslocation pore regulated by auto-ubiquitination and binding of misfolded proteins

V Vasic, N Denkert, CC Schmidt, D Riedel, A Stein… - Nature Cell …, 2020 - nature.com
During endoplasmic-reticulum-associated protein degradation (ERAD), misfolded proteins
are polyubiquitinated, extracted from the ER membrane and degraded by the proteasome …

Testing for a change in mean after changepoint detection

S Jewell, P Fearnhead, D Witten - Journal of the Royal Statistical …, 2022 - academic.oup.com
While many methods are available to detect structural changes in a time series, few
procedures are available to quantify the uncertainty of these estimates post-detection. In this …

Random forests for change point detection

M Londschien, P Bühlmann, S Kovács - Journal of Machine Learning …, 2023 - jmlr.org
We propose a novel multivariate nonparametric multiple change point detection method
using classifiers. We construct a classifier log-likelihood ratio that uses class probability …

Heterogeneous change point inference

F Pein, H Sieling, A Munk - … the Royal Statistical Society Series B …, 2017 - academic.oup.com
We propose, a heterogeneous simultaneous multiscale change point estimator called 'H-
SMUCE'for the detection of multiple change points of the signal in a heterogeneous …

FDR-control in multiscale change-point segmentation

H Li, A Munk, H Sieling - 2016 - projecteuclid.org
Fast multiple change-point segmentation methods, which additionally provide faithful
statistical statements on the number, locations and sizes of the segments, have recently …

Statistics and related topics in single-molecule biophysics

H Qian, SC Kou - Annual review of statistics and its application, 2014 - annualreviews.org
Since the universal acceptance of atoms and molecules as the fundamental constituents of
matter in the early-twentieth century, molecular physics, chemistry, and molecular biology …