Research models for studying vascular calcification

J Herrmann, M Babic, M Tölle, M van der Giet… - International journal of …, 2020 - mdpi.com
Calcification of the vessel wall contributes to high cardiovascular morbidity and mortality.
Vascular calcification (VC) is a systemic disease with multifaceted contributing and inhibiting …

Curcumin ameliorates kidney function and oxidative stress in experimental chronic kidney disease

BH Ali, S Al‐Salam, Y Al Suleimani… - Basic & Clinical …, 2018 - Wiley Online Library
Chronic kidney disease (CKD) is known to involve inflammation, oxidative stress and
apoptosis. Here, we investigated the impact of curcumin (diferuloyl methane, a phenolic …

CKD-MBD: from the pathogenesis to the identification and development of potential novel therapeutic targets

RM Elias, MA Dalboni, ACE Coelho… - Current Osteoporosis …, 2018 - Springer
Abstract Purpose of Review Although we have seen tremendous advances in the
comprehension of CKD-MBD pathophysiology during the last few years, this was not …

Adenine-induced chronic kidney disease induces a similar skeletal phenotype in male and female C57BL/6 mice with more severe deficits in cortical bone properties …

CE Metzger, EA Swallow, AJ Stacy, MR Allen - PLoS One, 2021 - journals.plos.org
Chronic kidney disease (CKD) causes bone loss, particularly in cortical bone, through
formation of cortical pores which lead to skeletal fragility. Animal models of CKD have shown …

A novel fluorescent probe-based flow cytometric assay for mineral-containing nanoparticles in serum

ER Smith, TD Hewitson, MMX Cai, P Aghagolzadeh… - Scientific reports, 2017 - nature.com
Calciprotein particles, nanoscale aggregates of insoluble mineral and binding proteins,
have emerged as potential mediators of phosphate toxicity in patients with Chronic Kidney …

[HTML][HTML] The effect of sildenafil on rats with adenine—Induced chronic kidney disease

BH Ali, M Al Za'abi, SA Adham, Y Al Suleimani… - Biomedicine & …, 2018 - Elsevier
The erectile dysfunction drug sildenafil has cardiopulmonary protective actions, and a
nephroprotective action in cisplatin and ischemia-reperfusion–induced acute kidney injury …

Chronic treatment of curcumin improves hepatic lipid metabolism and alleviates the renal damage in adenine-induced chronic kidney disease in Sprague-Dawley rats

H Ghelani, V Razmovski-Naumovski, D Chang… - BMC nephrology, 2019 - Springer
Background Chronic kidney disease (CKD), including nephrotic syndrome, is a major cause
of cardiovascular morbidity and mortality. The literature indicates that CKD is associated with …

Diosmin, a citrus fruit-derived phlebotonic bioflavonoid protects rats from chronic kidney disease-induced loss of bone mass and strength without deteriorating the …

S Sharma, K Porwal, C Kulkarni, S Pal, P Sihota… - Food & Function, 2022 - pubs.rsc.org
Kidney Disease Improving Global Outcomes (KDIGO) 2017 Clinical Practice Guideline has
recommended treatment decisions for patients with chronic kidney disease (CKD) with …

[HTML][HTML] Gum acacia improves renal function and ameliorates systemic inflammation, oxidative and nitrosative stress in streptozotocin-induced diabetes in rats with …

A Za'abi, S Al Salam, Y Al Suleimani, P Manoj… - Cellular Physiology and …, 2018 - karger.com
Background/Aims: The effect of treatment with gum acacia (GA), a prebiotic shown
previously to ameliorate chronic kidney disease (CKD), in diabetic and non–diabetic rats …

The Nephroprotective Effects of Hibiscus sabdariffa Leaf and Ellagic Acid in Vitro and in Vivo Models of Hyperuricemic Nephropathy

JH Chen, PT Wu, CC Chyau, PH Wu… - Journal of Agricultural …, 2022 - ACS Publications
Hyperuricemic nephropathy (HN) is caused by urate crystals that get deposited in the kidney
and contribute to renal fibrosis. Uric acid (UA) has been proven to directly cause renal …