[HTML][HTML] Gene therapy in cancer treatment: why go nano?

C Roma-Rodrigues, L Rivas-García, PV Baptista… - Pharmaceutics, 2020 - mdpi.com
The proposal of gene therapy to tackle cancer development has been instrumental for the
development of novel approaches and strategies to fight this disease, but the efficacy of the …

Strategies for targeting gene therapy in cancer cells with tumor-specific promoters

M Montaño-Samaniego, DM Bravo-Estupiñan… - Frontiers in …, 2020 - frontiersin.org
Cancer is the second cause of death worldwide, surpassed only by cardiovascular diseases,
due to the lack of early diagnosis, and high relapse rate after conventional therapies …

Investigating the regulatory role of miRNAs as silent conductors in the management of pathogenesis and therapeutic resistance of pancreatic cancer

AI Abulsoud, SS Elshaer, NM Abdelmaksoud… - … -Research and Practice, 2023 - Elsevier
Pancreatic cancer (PC) has the greatest mortality rate of all the main malignancies. Its
advanced stage and poor prognosis place it at the bottom of all cancer sites. Hence …

Bioanalytical applications of graphene quantum dots for circulating cell-free nucleic acids: a review

P Ratre, B Jain, R Kumari, S Thareja, R Tiwari… - ACS …, 2022 - ACS Publications
Graphene quantum dots (GQDs) are carbonaceous nanodots that are natural crystalline
semiconductors and range from 1 to 20 nm. The broad range of applications for GQDs is …

Implications of photodynamic cancer therapy: An overview of PDT mechanisms basically and practically

N Sobhani, AA Samadani - Journal of the Egyptian National Cancer …, 2021 - Springer
Background Tumor eradication is one of the most important challengeable categories in
oncological studies. In this account, besides the molecular genetics methods including cell …

[HTML][HTML] Nutrition management in acute pancreatitis: Clinical practice consideration

N Lakananurak, L Gramlich - World journal of clinical cases, 2020 - ncbi.nlm.nih.gov
Acute pancreatitis (AP) is a common gastrointestinal disease and the leading cause of
hospital admission and healthcare burden among gastrointestinal disorders in many …

Electrochemical nanobiosensors for detection of breast cancer biomarkers

V Gajdosova, L Lorencova, P Kasak, J Tkac - Sensors, 2020 - mdpi.com
This comprehensive review paper describes recent advances made in the field of
electrochemical nanobiosensors for the detection of breast cancer (BC) biomarkers such as …

The current state of MiRNAs as biomarkers and therapeutic tools

I Gareev, O Beylerli, G Yang, J Sun, V Pavlov… - Clinical and …, 2020 - Springer
MicroRNAs (miRNAs) are non-coding RNAs with a length of 18–22 nucleotides that regulate
about a third of the human genome at the post-transcriptional level. MiRNAs are involved in …

Interference reduction biosensing strategy for highly sensitive microRNA detection

F Chen, G Li, C Wu, L Wang, CN Ko, DL Ma… - Analytical …, 2022 - ACS Publications
MicroRNAs are potential biomarkers for human cancers and other diseases due to their
roles as post-transcriptional regulators for gene expression. However, the detection of …

MicroRNA-326 attenuates immune escape and prevents metastasis in lung adenocarcinoma by targeting PD-L1 and B7-H3

L Shao, Q He, J Wang, F He, S Lin, L Wu, Y Gao… - Cell Death …, 2021 - nature.com
Tumor-infiltrating T cells are highly expressive of inhibitory receptor/immune checkpoint
molecules that bind to ligand expressed by tumor cells and antigen-presenting cells, and …