Codon usage analysis of pro-apoptotic bim gene isoforms
Background: Bim is a Bcl-2 homology 3 (BH3)-only proteins, a group of pro-apoptotic
proteins involved in physiological and pathological conditions. Both the overexpression and …
proteins involved in physiological and pathological conditions. Both the overexpression and …
Application of codon usage and context analysis in genes up-or down-regulated in neurodegeneration and cancer to combat comorbidities
Introduction Neurodegeneration and cancer present in comorbidities with inverse effects
due to the expression of genes and pathways acting in opposition. Identifying and studying …
due to the expression of genes and pathways acting in opposition. Identifying and studying …
Molecular Dissection of Herpes Simplex Virus Type 1 to Elucidate Molecular Mechanisms Behind Latency and Comparison of Its Codon Usage Patterns with Genes …
P Gurjar, AA Khan, AM Alanazi… - Journal of …, 2024 - content.iospress.com
Background: Herpes simplex virus type 1 (HSV-1) is associated with Alzheimer's disease,
which goes into a cycle of latency and reactivation. The present study was envisaged to …
which goes into a cycle of latency and reactivation. The present study was envisaged to …
Codon usage bias correlates with gene length in neurodegeneration associated genes
Codon usage analysis is a crucial part of molecular characterization and is used to
determine the factors affecting the evolution of a gene. The length of a gene is an important …
determine the factors affecting the evolution of a gene. The length of a gene is an important …
Codon usage is influenced by compositional constraints in genes associated with dementia
Dementia is a clinical syndrome characterized by progressive cognitive decline, and the
symptoms could be gradual, persistent, and progressive. In the present study, we …
symptoms could be gradual, persistent, and progressive. In the present study, we …
Insights into synonymous codon usage bias in hepatitis C virus and its adaptation to hosts
Hepatitis C virus (HCV) is enveloped RNA virus, encoding for a polyprotein that is processed
by cellular proteases. The virus is responsible for liver cirrhosis, allograft rejection, and …
by cellular proteases. The virus is responsible for liver cirrhosis, allograft rejection, and …
Synonymous codon variant analysis for autophagic genes dysregulated in neurodegeneration
Neurodegenerative disorders are often a culmination of the accumulation of abnormally
folded proteins and defective organelles. Autophagy is a process of removing these …
folded proteins and defective organelles. Autophagy is a process of removing these …
An insight into codon pattern analysis of autophagy genes associated with virus infection
S Singhal, U Kumar, T Alqahtani… - Current …, 2023 - ingentaconnect.com
Introduction: Apoptosis and autophagy are the two fundamental processes involved in
maintaining homeostasis, and a common stimulus may initiate the processes. Autophagy …
maintaining homeostasis, and a common stimulus may initiate the processes. Autophagy …
In-silico Codon Context and Synonymous Usage Analysis of Genes for Molecular Mechanisms Inducing Autophagy and Apoptosis with Reference to …
R Khandia, P Gurjar, V Romashchenko… - Journal of …, 2024 - content.iospress.com
Background: Autophagy and apoptosis are cellular processes that maintain cellular
homeostasis and remove damaged or aged organelles or aggregated and misfolded …
homeostasis and remove damaged or aged organelles or aggregated and misfolded …
Codon pattern and compositional constraints determination of genes associated with chronic periodontitis
Genome-wide association studies showed the relationship of NIN, ABHD12B, WHAMM,
AP3B2, and SIGLEC5 with chronic periodontitis. The study's objective was to investigate …
AP3B2, and SIGLEC5 with chronic periodontitis. The study's objective was to investigate …