Sarcopenia predicts worse postoperative outcomes and decreased survival rates in patients with colorectal cancer: a systematic review and meta-analysis

M Trejo-Avila, K Bozada-Gutiérrez… - International journal of …, 2021 - Springer
Purpose Previous studies have shown an association of sarcopenia with adverse short-and
long-term outcomes in multiple gastrointestinal cancer types. We aimed to investigate the …

Implications of low muscle mass across the continuum of care: a narrative review

CM Prado, SA Purcell, C Alish, SL Pereira… - Annals of …, 2018 - Taylor & Francis
Abnormalities in body composition can occur at any body weight. Low muscle mass is a
predictor of poor morbidity and mortality and occurs in several populations. This narrative …

Explaining the obesity paradox: the association between body composition and colorectal cancer survival (C-SCANS Study)

BJ Caan, JA Meyerhardt, CH Kroenke, S Alexeeff… - … , biomarkers & prevention, 2017 - AACR
Background: Body composition may partially explain the U-shaped association between
body mass index (BMI) and colorectal cancer survival. Methods: Muscle and adiposity at …

Association of low muscle mass and low muscle radiodensity with morbidity and mortality for colon cancer surgery

J Xiao, BJ Caan, EMC Feliciano, JA Meyerhardt… - JAMA …, 2020 - jamanetwork.com
Importance Given the risks of postoperative morbidity and its consequent economic burden
and impairment to patients undergoing colon resection, evaluating risk factors associated …

Sarcopenia is an independent predictor of complications after colorectal cancer surgery

R Nakanishi, E Oki, S Sasaki, K Hirose, T Jogo… - Surgery today, 2018 - Springer
Purpose The significance of sarcopenia after colorectal cancer (CRC) resection has only
been discussed with relatively small samples or short follow-up periods. This study aimed to …

The impact of muscle and adipose tissue on long-term survival in patients with stage I to III colorectal cancer

JJ Hopkins, RL Reif, DL Bigam… - Diseases of the Colon …, 2019 - journals.lww.com
BACKGROUND: Computed tomography-derived body composition parameters are
emerging prognostic factors in colorectal cancer. OBJECTIVE: This study aimed to …

Assessment of computed tomography (CT)-defined muscle and adipose tissue features in relation to short-term outcomes after elective surgery for colorectal cancer: a …

L Martin, J Hopkins, G Malietzis, JT Jenkins… - Annals of surgical …, 2018 - Springer
Background Sarcopenia, visceral obesity (VO), and reduced muscle radiodensity
(myosteatosis) are suggested risk factors for postoperative morbidity in colorectal cancer …

The malnourished surgery patient: a silent epidemic in perioperative outcomes?

DGA Williams, J Molinger… - Current Opinion in …, 2019 - journals.lww.com
The recent publication of new surgical nutrition guidelines, the PONS score, and use of LBM
assessments will allow better identification and earlier intervention on perioperative …

Muscle radiodensity and mortality in patients with colorectal cancer

CH Kroenke, CM Prado, JA Meyerhardt, EK Weltzien… - Cancer, 2018 - Wiley Online Library
BACKGROUND Low skeletal muscle radiodensity (SMD) is related to higher mortality in
several cancers, but the association with colorectal cancer (CRC) prognosis is unclear …

The obesity paradox in cancer: how important is muscle?

EM Cespedes Feliciano, CH Kroenke… - Annual review of …, 2018 - annualreviews.org
Although higher body mass index (BMI) increases the incidence of many cancers, BMI can
also exhibit a null or U-shaped relationship with survival among patients with existing …