Depression is frequent in older individuals and is often associated with cognitive impairment
and increasing risk of subsequent dementia. Late-life depression (LLD) has a negative …

Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in
neurodegenerative dementias. The most common symptoms are apathy, depression …

Associations between age-related neuropathological lesions and adult-onset lifetime major
depressive disorder (a-MDD), late-life MDD (LLD), or depressive symptoms close to death …

Abstract Background Depressive symptoms in Alzheimer's disease (AD) predict worse
cognitive and functional outcomes. Both AD and major depression inflammatory processes …

We investigated the potential of machine learning for diagnostic classification in late-life
major depression based on an advanced whole brain white matter segmentation framework …

Background Acute exacerbation of chronic obstructive pulmonary disease (COPD) is an
important event in the process of disease management. Early identification of high-risk …

Introduction This study aimed to investigate the cognitive profile and prospective cognitive
changes in non-demented adults with elevated Modified Dementia Risk Scores (MDRS) …

Multiple system atrophy is a neurodegenerative disease with α-synuclein pathology
predominating in the striatonigral and olivopontocerebellar systems. Mixed pathologies are …

Objectives With a shift in global demographic trends favouring the older population,
depression, which is increasingly common to older adults, is fast becoming a significant …

Subjective cognitive decline (SCD) is defined as a self-perception of a progressive cognitive
impairment, which is not detected objectively through neuropsychological tests. The …