Impact of particle size and polydispersity index on the clinical applications of lipidic nanocarrier systems

M Danaei, M Dehghankhold, S Ataei… - Pharmaceutics, 2018 - mdpi.com
Lipid-based drug delivery systems, or lipidic carriers, are being extensively employed to
enhance the bioavailability of poorly-soluble drugs. They have the ability to incorporate both …

Measurement of anticancer, antidiabetic and anticholinergic properties of sumac (Rhus coriaria): analysis of its phenolic compounds by LC–MS/MS

H Tohma, A Altay, E Köksal, AC Gören… - Journal of Food …, 2019 - Springer
The present study aimed to investigate Sumac (Rhus coriaria) for anticancer, antidiabetic,
anticholinergic activities and total phenolic and flavonoid contents. Two solvents, water and …

Fabrication of cellulose nanocrystals as potential anticancer drug delivery systems for colorectal cancer treatment

M Yusefi, MLK Soon, SY Teow, EI Monchouguy… - International Journal of …, 2022 - Elsevier
Polysaccharide nanocrystals have great potential to be used as improved drug carriers due
to their low cost, high biodegradability, and biocompatibility. This study reports the synthesis …

[HTML][HTML] Enhanced anti-lung carcinoma and anti-biofilm activity of fungal molecules mediated biogenic zinc oxide nanoparticles conjugated with β-D-glucan from …

K Saravanakumar, E Jeevithan, X Hu… - … of Photochemistry and …, 2020 - Elsevier
This work reports the optimization, synthesis, characterization, anticancer, and antibacterial
activity of the Trichoderma-β-D-glucan‑zinc oxide nanoparticles (T-β-D-glu-ZnO NPs). Firstly …

Untargeted Metabolomic Approach of Curcuma longa to Neurodegenerative Phytocarrier System Based on Silver Nanoparticles

AE Segneanu, G Vlase, AT Lukinich-Gruia, DD Herea… - Antioxidants, 2022 - mdpi.com
Curcuma is one of the most famous medicinal and tropical aromatic plants. Its health
benefits have been appreciated and exploited in traditional Asian medicine since ancient …

Phyto-drug conjugated nanomaterials enhance apoptotic activity in cancer

K Vimala, S Kannan - Advances in Protein Chemistry and Structural Biology, 2021 - Elsevier
Cancer continues to be one of the leading causes of death worldwide and is a major
obstacle to increased life expectancy. However, survival has not improved significantly with …

Formulation, characterization and cytotoxicity effects of novel thymoquinone-PLGA-PF68 nanoparticles

NS Noor, NHM Kaus, MR Szewczuk… - International journal of …, 2021 - mdpi.com
Thymoquinone has anti-cancer properties. However, its application for clinical use is limited
due to its volatile characteristics. The current study aims to develop a polymeric …

Chlorambucil-loaded graphene-oxide-based nano-vesicles for cancer therapy

S Kumari, A Nehra, K Gupta, A Puri, V Kumar, KP Singh… - Pharmaceutics, 2023 - mdpi.com
In this study, the authors have designed biocompatible nano-vesicles using graphene oxide
(GO) for the release of chlorambucil (CHL) drugs targeting cancerous cells. The GO sheets …

Mitochondria-targeted nanoparticles based on glycated oat protein for enhanced curcumin bioavailability and antioxidant activity

L Zhong, J Tian, Q Hu, L Zhao, Q Zhan, M Zhao - Food Bioscience, 2024 - Elsevier
Curcumin is a hydrophobic dietary supplement and can mitigate oxidative damage.
However, the low bioavailability of curcumin impedes its application in functional foods …

Sustained delivery of andrographolide from 3D porous scaffolds imparting anticancer activity

SK Lavanya, SK Rao, P Rajapriya, S Patil… - Journal of Drug Delivery …, 2022 - Elsevier
The sustained release of therapeutic drugs into the tumor environment is gaining much
attention due to its advantages like low systemic side effects, high efficiency, and cost …