Diagnosis and management of axial spondyloarthritis (axSpA) has vastly improved over the
past two decades. With advances in the discernment of immunopathogenesis of this …

1.2. Definitions Ulcerative colitis [UC] is a chronic inflammatory condition that causes
continuous mucosal inflammation of the colon, usually without granulomas on biopsy. It …

To update and integrate the recommendations for ankylosing spondylitis and the
recommendations for the use of tumour necrosis factor inhibitors (TNFi) in axial …

Background Biological disease-modifying anti-rheumatic drugs (bDMARDs) are
recommended for radiographic axial spondyloarthritis, otherwise known as ankylosing …

This paper is the second in a series of two publications relating to the European Crohn's and
Colitis Organisation [ECCO] evidence-based consensus on the diagnosis and management …

Background Secukinumab is an anti–interleukin-17A monoclonal antibody that has been
shown to control the symptoms of ankylosing spondylitis in a phase 2 trial. We conducted …

The term axial spondyloarthritis covers both patients with non-radiographic and radiographic
axial spondyloarthritis, which is also termed ankylosing spondylitis. The disease usually …

Gut inflammation is strongly associated with spondyloarthritis (SpA), as exemplified by the
high prevalence of inflammatory bowel disease (IBD) and the even higher occurrence of …

Objectives To compare efficacy and safety of various doses of tofacitinib, an oral Janus
kinase inhibitor, with placebo in patients with active ankylosing spondylitis (AS, radiographic …

Objectives A systematic review was conducted to explore the immunogenicity of biologic
agents across inflammatory diseases and its potential impact on efficacy/safety. Methods …