Purpose This paper reviews 10 principles of experience-dependent neural plasticity and
considerations in applying them to the damaged brain. Method Neuroscience research …

Many studies in human and animal models have shown that neural plasticity compensates
for the loss of motor function after stroke. However, neural plasticity concerning …

Background Stroke rehabilitation with different exercise paradigms has been investigated,
but which one is more effective in facilitating motor recovery and up-regulating brain …

Voluntary exercise, treadmill activity, skills training, and forced limb use have been utilized in
animal studies to promote brain plasticity and functional change. Motor enrichment may …

Rodents are the most widely used experimental animals in stroke research due to their
similar vascular anatomy, high reproductive rates, and availability of transgenic models …

Behavioral experience is at work modifying the structure and function of the brain throughout
the lifespan, but it has a particularly dramatic influence after brain injury. This review …

Neonatal stroke is a condition that leads to disability in later life, and as yet there is no
effective treatment. Recently, erythropoietin (EPO) has been shown to be cytoprotective …

Matrix metalloproteinase-9 (MMP-9) participates in the disregulation of blood–brain barrier
during hemorrhagic transformation, and exacerbates brain injury after cerebral ischemia …

Recent years have seen a proliferation of animal and human studies that have associated
significant changes in regional brain physiology with sustained altered environmental or …

Background and Purpose. Exercise and rehabilitative training each have been implicated in
the promotion of restorative neural plasticity after cerebral injury. Because motor skill training …