How does the immune system enter the brain?

JA Mapunda, H Tibar, W Regragui… - Frontiers in …, 2022 - frontiersin.org
Multiple Sclerosis (MS) is considered the most frequent inflammatory demyelinating disease
of the central nervous system (CNS). It occurs with a variable prevalence across the world. A …

Understanding the rise of cardiometabolic diseases in low-and middle-income countries

JJ Miranda, T Barrientos-Gutierrez, C Corvalan… - Nature medicine, 2019 - nature.com
Increases in the prevalence of noncommunicable diseases (NCDs), particularly
cardiometabolic diseases such as cardiovascular disease, stroke and diabetes, and their …

Burden of non-communicable diseases in sub-Saharan Africa, 1990–2017: results from the Global Burden of Disease Study 2017

HN Gouda, F Charlson, K Sorsdahl… - The Lancet global …, 2019 - thelancet.com
Background Although the burden of disease in sub-Saharan Africa continues to be
dominated by infectious diseases, countries in this region are undergoing a demographic …

Diabetes in developing countries

A Misra, H Gopalan, R Jayawardena… - Journal of …, 2019 - Wiley Online Library
There has been a rapid escalation of type 2 diabetes (T2D) in developing countries, with
varied prevalence according to rural vs urban habitat and degree of urbanization. Some …

[HTML][HTML] Prevalence of obesity, hypertension, and diabetes, and cascade of care in sub-Saharan Africa: a cross-sectional, population-based study in rural and urban …

AJ Price, AC Crampin, A Amberbir… - The lancet Diabetes & …, 2018 - thelancet.com
Summary Background Sub-Saharan Africa is in rapid demographic transition, and non-
communicable diseases are increasingly important causes of morbidity and mortality. We …

Review of ongoing activities and challenges to improve the care of patients with type 2 diabetes across Africa and the implications for the future

B Godman, D Basu, Y Pillay, JC Mwita… - Frontiers in …, 2020 - frontiersin.org
Background There has been an appreciable increase in the number of people in Africa with
metabolic syndrome and Type 2 diabetes (T2DM) in recent years as a result of a number of …

Ongoing initiatives to improve the quality and efficiency of medicine use within the public healthcare system in South Africa; a preliminary study

JC Meyer, N Schellack, J Stokes, R Lancaster… - Frontiers in …, 2017 - frontiersin.org
Introduction: South Africa has an appreciable burden of both communicable and non-
communicable diseases as well as high maternal, neonatal, and child morbidity. In recent …

Type 2 diabetes mellitus in sub-Saharan Africa: challenges and opportunities

AA Motala, JC Mbanya, K Ramaiya, FJ Pirie… - Nature Reviews …, 2022 - nature.com
Type 2 diabetes mellitus (T2DM), which was once thought to be rare in sub-Saharan Africa
(SSA), is now well established in this region. The SSA region is undergoing a rapid but …

Short-and long-read metagenomics of urban and rural South African gut microbiomes reveal a transitional composition and undescribed taxa

FB Tamburini, D Maghini, OH Oduaran… - Nature …, 2022 - nature.com
Human gut microbiome research focuses on populations living in high-income countries and
to a lesser extent, non-urban agriculturalist and hunter-gatherer societies. The scarcity of …

The WHO global strategy for oral health: an opportunity for bold action

H Benzian, CC Guarnizo-Herreño, C Kearns… - The Lancet, 2021 - thelancet.com
1 Seiglie JA, Marcus ME, Ebert C, et al. Diabetes prevalence and its relationship with
education, wealth, and BMI in 29 low-and middleincome countries. Diabetes Care 2020; 43 …