Prevalence of psychotropic polypharmacy in nursing home residents with dementia: a meta-analysis

DJ Jester, V Molinari, JC Zgibor… - International …, 2021 - cambridge.org
Objectives: Nursing home (NH) residents with dementia is exposed to high rates of
psychotropic prescriptions. Our objectives were to:(1) pool the prevalence estimates of …

Pharmacogenetic considerations when prescribing cholinesterase inhibitors for the treatment of Alzheimer's disease

R Cacabelos - Expert Opinion on Drug Metabolism & Toxicology, 2020 - Taylor & Francis
Introduction Cholinergic dysfunction, demonstrated in the late 1970s and early 1980s, led to
the introduction of acetylcholinesterase inhibitors (AChEIs) in 1993 (Tacrine) to enhance …

Prevalence of central nervous system–active polypharmacy among older adults with dementia in the US

DT Maust, J Strominger, HM Kim, KM Langa… - Jama, 2021 - jamanetwork.com
Importance Community-dwelling older adults with dementia have a high prevalence of
psychotropic and opioid use. In these patients, central nervous system (CNS)–active …

Fatigue in Alzheimer's disease: biological basis and clinical management—a narrative review

D Angioni, J Raffin, PJ Ousset, J Delrieu… - Aging Clinical and …, 2023 - Springer
Background Fatigue is a common symptom in neurodegenerative diseases and is
associated with decreased cognitive performances. A full knowledge of the causes and …

Therapeutic dilemma's: antipsychotics use for neuropsychiatric symptoms of dementia, delirium and insomnia and risk of falling in older adults, a clinical review

N Korkatti-Puoskari, M Tiihonen… - European Geriatric …, 2023 - Springer
Purpose Because of the common and increasing use of antipsychotics in older adults, we
aim to summarize the current knowledge on the causes of antipsychotic-related risk of falls …

[HTML][HTML] Symptomatic and Preventive Medication Use before and after Alzheimer's Disease Diagnosis: A 10-Year Matched Cohort Study

SJ Liau, JS Bell, S Lalic, AM Tolppanen… - Journal of the American …, 2024 - Elsevier
Objective To investigate longitudinal changes in symptomatic and preventive medication
use among community-dwelling people with and without Alzheimer's disease (AD) 5 years …

Do acetylcholinesterase inhibitors prevent or delay psychotropic prescribing in people with dementia? Analyses of the Swedish Dementia Registry

ECK Tan, K Johnell, JS Bell, S Garcia-Ptacek… - The American journal of …, 2020 - Elsevier
Objectives To investigate whether acetylcholinesterase inhibitor (AChEI) use prevents or
delays subsequent initiation of psychotropic medications in people with Alzheimer's disease …

The relationship between antipsychotics, cognitive enhancers, and major adverse cardiovascular/cerebrovascular events (MACCE) in older adults with behavioral and …

HM DeMercy, CA Brenner - Drugs & Aging, 2024 - Springer
Abstract Background and Objectives Antipsychotics and cognitive enhancers are often used
to treat psychosis and behavioral disturbances in individuals with dementia; however, these …

Polypharmacy in Treatment of Behavioral Issues in Dementia—Use of Atypical Antipsychotics

J Jalil, P Nazarian… - Clinics in Geriatric …, 2022 - geriatric.theclinics.com
Polypharmacy in Treatment of Behavioral Issues in Dementia—Use of Atypical
Antipsychotics - Clinics in Geriatric Medicine Skip to Main Content Skip to Main Menu …

Psychotropic drug prescription rates in primary care for people with dementia from recorded diagnosis onwards

KJ Joling, M Koppel, HPJ Van Hout… - … journal of geriatric …, 2021 - Wiley Online Library
Background Psychotropic drugs are frequently prescribed to people with dementia in
nursing homes although severe adverse events and side effects are common. Less is known …