Bioinformatics approaches for understanding the consequences of mutations to the binding affinity of protein–DNA complexes
Protein–nucleic acid interactions are inevitable in maintaining the homeostasis of cells. It is
important to have a quantitative understanding of these interactions, generally described in …
important to have a quantitative understanding of these interactions, generally described in …
Prediction of Protein‒DNA Interface Hot Spots Based on Empirical Mode Decomposition and Machine Learning
Z Fang, Z Li, M Li, Z Yue, K Li - Genes, 2024 - mdpi.com
Protein–DNA complex interactivity plays a crucial role in biological activities such as gene
expression, modification, replication and transcription. Understanding the physiological …
expression, modification, replication and transcription. Understanding the physiological …
Protein-DNA interface hotspots prediction based on fusion features of embeddings of protein language model and handcrafted features
X Li, GA Wang, Z Wei, H Wang, X Zhu - Computational Biology and …, 2023 - Elsevier
The identification of hotspot residues at the protein-DNA binding interfaces plays a crucial
role in various aspects such as drug discovery and disease treatment. Although …
role in various aspects such as drug discovery and disease treatment. Although …
of mutations to the binding affinity of protein-DNA complexes
K Harini¹, A Phogat¹, MM Gromiha - … : Consequences On Structure …, 2024 - books.google.com
Protein-nucleic acid interactions are inevitable in maintaining the homeostasis of cells. It is
important to have a quantitative understanding of these interactions, generally described in …
important to have a quantitative understanding of these interactions, generally described in …