[HTML][HTML] Protective effect of novel angiotensin receptor neprilysin inhibitor S086 on target organ injury in spontaneously hypertensive rats
Y Xiao, ZY Zhou, JC Sun, W Xing, J Yan, WJ Xu… - Biomedicine & …, 2024 - Elsevier
Background Hypertension is a clinical syndrome characterized by elevated systemic arterial
blood pressure associated with injury to the heart, kidney, brain, and other organs …
blood pressure associated with injury to the heart, kidney, brain, and other organs …
A randomized, double-blind, placebo-controlled, single, and multiple dose-escalation Phase I clinical trial to investigate the safety, pharmacokinetic, and …
Y Hu, H Zhang, X Li, J Mai, L Yang, J Yan… - Expert Opinion on …, 2022 - Taylor & Francis
Background This study evaluated the safety, pharmacokinetic (PK), and pharmacodynamic
(PD) profiles of single ascending doses (SAD) and multiple ascending doses (MAD) of S086 …
(PD) profiles of single ascending doses (SAD) and multiple ascending doses (MAD) of S086 …
Efficacy and safety of sacubitril/allisartan for the treatment of primary hypertension: A phase 2 randomized, double-blind study
J Zhang, W Zhang, J Yan, Q Ge, XH Lu… - Hypertension …, 2023 - nature.com
This randomized, double-blind phase 2 study assessed the efficacy and safety of
sacubitril/allisartan, an angiotensin receptor neprilysin inhibitor, compared with placebo in …
sacubitril/allisartan, an angiotensin receptor neprilysin inhibitor, compared with placebo in …
Alopecia Universalis in an Elderly Chinese Man Induced by Sacubitril/Alisartan, a Novel Angiotensin Receptor-Neprilysin Inhibitor
Y Teng, Y Fan, D Shang, X Tao… - Journal of Inflammation …, 2023 - Taylor & Francis
Drug-induced alopecia areata is a rare adverse event wherein medications such as
antimicrobials, anticonvulsants, and biologics, trigger the premature transition of actively …
antimicrobials, anticonvulsants, and biologics, trigger the premature transition of actively …
The Role of NAD+ in Myocardial Ischemia-induced Heart Failure in Sprague-Dawley Rats and Beagles
Z Pei, C Yang, Y Guo, M Dong… - Current Pharmaceutical …, 2024 - ingentaconnect.com
Introduction: Nicotinamide adenine dinucleotide (NAD+) participates in various processes
that are dysregulated in cardiovascular diseases. Supplementation with NAD+ may be …
that are dysregulated in cardiovascular diseases. Supplementation with NAD+ may be …
Anti-hypertensive effect of a novel angiotensin II receptor neprilysin inhibitor (ARNi)-S086 in DSS rat model
J Sun, Y Xiao, W Xu, W Xing, F Du, M Tian… - Frontiers in …, 2024 - frontiersin.org
Introduction Angiotensin receptor-neprilysin inhibitor (ARNi), comprised of an angiotensin
receptor blocker (ARB) and a neprilysin inhibitor (NEPi), has established itself as a safe and …
receptor blocker (ARB) and a neprilysin inhibitor (NEPi), has established itself as a safe and …
Novas Terapêuticas na Insuficiência Cardíaca com Fração de Ejeção Reduzida: Revisão Sistemática
RD dos Anjos Dias - 2022 - search.proquest.com
Introdução: A insuficiência cardíaca (IC) é uma síndrome que tem sintomas e sinais típicos
resultantes da redução do débito cardíaco e/ou elevação das pressões intracardíacas em …
resultantes da redução do débito cardíaco e/ou elevação das pressões intracardíacas em …
Novas terapêuticas na insuficiência cardíaca com fração de ejeção reduzida: Revisão Sistemática
RDA Dias - ubibliorum.ubi.pt
Introdução: A insuficiência cardíaca (IC) é uma síndrome que tem sintomas e sinais típicos
resultantes da redução do débito cardíaco e/ou elevação das pressões intracardíacas em …
resultantes da redução do débito cardíaco e/ou elevação das pressões intracardíacas em …